Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744) …

GS Sheppard, L Wang, SD Fidanze… - Journal of Medicinal …, 2020 - ACS Publications
The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains
two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under …
被引用次数：91 相关文章

Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744) …

GS Sheppard, L Wang, SD Fidanze… - Journal of Medicinal …, 2020 - europepmc.org
The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains
two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under …

Discovery of N-Ethyl-4-[2-(4-fluoro-2, 6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl) phenyl]-6-methyl-7-oxo-1 H-pyrrolo [2, 3-c] pyridine-2-carboxamide (ABBV …

GS Sheppard, L Wang, SD Fidanze… - Journal of …, 2020 - pubmed.ncbi.nlm.nih.gov
The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains
two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under …

[引用][C] Discovery of N-Ethyl-4-[2-(4-fluoro-2, 6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl) phenyl]-6-methyl-7-oxo-1H-pyrrolo [2, 3-c] pyridine-2-carboxamide …

GS Sheppard, L Wang, SD Fidanze, LA Hasvold, D Liu… - J. Med. Chem., 2020 - osti.gov