Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation

DB Kum, H Vanrusselt, AA Sanchez, V Taverniti… - Hepatology, 2023 - journals.lww.com
Conclusions: Our study unravels a previously unknown mechanism of action for CAM-As
such as RG7907 in which HBc aggregation induces cell death, resulting in hepatocyte …
被引用次数：9 相关文章

Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.

DB Kum, H Vanrusselt, AA Sanchez… - Hepatology (Baltimore …, 2023 - hal.science
Effective therapies leading to a functional cure of chronic hepatitis B (CHB) are still lacking.
Class A capsid assembly modulators (CAM-As) are an attractive modality to address this …

Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation

DB Kum, H Vanrusselt, AA Sanchez, V Taverniti… - Hepatology - journals.lww.com
Conclusions: Our study unravels a previously unknown mechanism of action for CAM-As
such as RG7907 in which HBc aggregation induces cell death, resulting in hepatocyte …

Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation

DB Kum, H Vanrusselt, A Acosta Sanchez… - …, 2023 - lirias.kuleuven.be
BACKGROUND AND AIMS: Effective therapies leading to a functional cure for chronic
hepatitis B are still lacking. Class A capsid assembly modulators (CAM-As) are an attractive …

Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation

DB Kum, H Vanrusselt, A Acosta Sanchez… - …, 2023 - ingentaconnect.com
Background and Aims: Effective therapies leading to a functional cure for chronic hepatitis B
are still lacking. Class A capsid assembly modulators (CAM-As) are an attractive modality to …

Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.

DB Kum, H Vanrusselt, V Taverniti… - Hepatology …, 2023 - europepmc.org
Conclusions Our study unravels a previously unknown mechanism of action for CAM-As
such as RG7907 in which HBc aggregation induces cell death, resulting in hepatocyte …

Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation

DB Kum, H Vanrusselt, AA Sanchez… - Hepatology …, 2023 - pubmed.ncbi.nlm.nih.gov
Background and aims Effective therapies leading to a functional cure for chronic hepatitis B
are still lacking. Class A capsid assembly modulators (CAM-As) are an attractive modality to …