Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease

B Metaferia, T Cellmer… - Proceedings of the …, 2022 - National Acad Sciences
Stem cell transplantation and genetic therapies offer potential cures for patients with sickle
cell disease (SCD), but these options require advanced medical facilities and are expensive …

Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.

B Metaferia, T Cellmer, EB Dunkelberger… - Proceedings of the …, 2022 - europepmc.org
Results Images of Sickle Trait Cells upon Deoxygenation. Fig. 1 shows three typical images
at 13 h after the start of deoxygenation: one for the negative control with 85% of cells sickled …

Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease

B Metaferia, T Cellmer… - Proceedings of the …, 2022 - pubmed.ncbi.nlm.nih.gov
Stem cell transplantation and genetic therapies offer potential cures for patients with sickle
cell disease (SCD), but these options require advanced medical facilities and are expensive …

[HTML][HTML] Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease

B Metaferia, T Cellmer, EB Dunkelberger… - Proceedings of the …, 2022 - ncbi.nlm.nih.gov
Results Images of Sickle Trait Cells upon Deoxygenation. Fig. 1 shows three typical images
at 13 h after the start of deoxygenation: one for the negative control with 85% of cells sickled …

Phenotypic screening of the ReFrame Drug Repurposing Library to discover new drugs for treating sickle cell disease

B Metaferia, T Cellmer, EB Dunkelberger, Q Li… - bioRxiv, 2022 - biorxiv.org
Stem-cell transplantation and genetic therapies offer potential cures for patients with sickle
cell disease (SCD) but these options require advanced medical facilities and are expensive …

Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease

B Metaferia, T Cellmer… - Proceedings of the …, 2022 - ui.adsabs.harvard.edu
The majority of patients suffering from sickle cell disease live in underresourced countries.
Consequently, advanced medical facilities required for curative therapies, such as stem cell …

Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.

B Metaferia, T Cellmer, EB Dunkelberger… - Proceedings of the …, 2022 - europepmc.org
Stem cell transplantation and genetic therapies offer potential cures for patients with sickle
cell disease (SCD), but these options require advanced medical facilities and are expensive …