Machine-directed evolution of an imine reductase for activity and stereoselectivity

EJ Ma, E Siirola, C Moore, A Kummer, M Stoeckli… - ACS …, 2021 - ACS Publications
Biocatalysis is an effective tool to access chiral molecules that are otherwise hard to
synthesize or purify. Time-efficient processes are needed to develop enzymes that …

Simultaneous machine-directed evolution of an imine reductase for activity and stereoselectivity

C Moore, EM Siirola, E Ma, A Kummer, L Siegrist… - ACS …, 2021 - oak.novartis.com
Biocatalysis is an effective tool to access small quantities of chiral molecules that are
otherwise hard to synthesize or purify. A time-efficient process is needed to develop an …

Simultaneous machine-directed evolution of an imine reductase for activity and stereoselectivity

C Moore, EM Siirola, E Ma, A Kummer, L Siegrist… - ACS …, 2021 - oak.novartis.com
Biocatalysis is an effective tool to access small quantities of chiral molecules that are
otherwise hard to synthesize or purify. A time-efficient process is needed to develop an …