Identification of a pyridoxine-derived small-molecule inhibitor targeting dengue virus RNA-dependent RNA polymerase

HT Xu, SP Colby-Germinario… - Antimicrobial agents …, 2016 - Am Soc Microbiol
The viral RNA-dependent RNA polymerase (RdRp) activity of the dengue virus (DENV) NS5
protein is an attractive target for drug design. Here, we report the identification of a novel …

Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase

HT Xu, SP Colby-Germinario, S Hassounah… - Antimicrobial Agents …, 2016 - cir.nii.ac.jp
抄録< jats: title> ABSTRACT</jats: title>< jats: p> The viral RNA-dependent RNA polymerase
(RdRp) activity of the dengue virus (DENV) NS5 protein is an attractive target for drug …

[HTML][HTML] Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase

HT Xu, SP Colby-Germinario… - Antimicrobial Agents …, 2016 - ncbi.nlm.nih.gov
The viral RNA-dependent RNA polymerase (RdRp) activity of the dengue virus (DENV) NS5
protein is an attractive target for drug design. Here, we report the identification of a novel …

Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase

HT Xu, SP Colby-Germinario… - Antimicrobial …, 2015 - pubmed.ncbi.nlm.nih.gov
The viral RNA-dependent RNA polymerase (RdRp) activity of the dengue virus (DENV) NS5
protein is an attractive target for drug design. Here, we report the identification of a novel …

[PDF][PDF] Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase

HT Xu, SP Colby-Germinario… - Antimicrob Agents …, 2015 - researchgate.net
MATERIALS AND METHODS Reagents and nucleic acids. The () 3= untranscribed region [()
3= UTR] RNA, which contains the last 380 nucleotides (nt) of the negative strand of DENV2 …

Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.

HT Xu, SP Colby-Germinario, S Hassounah… - Antimicrobial Agents …, 2015 - europepmc.org
The viral RNA-dependent RNA polymerase (RdRp) activity of the dengue virus (DENV) NS5
protein is an attractive target for drug design. Here, we report the identification of a novel …

Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.

HT Xu, SP Colby-Germinario, S Hassounah… - Antimicrobial Agents …, 2015 - europepmc.org
The viral RNA-dependent RNA polymerase (RdRp) activity of the dengue virus (DENV) NS5
protein is an attractive target for drug design. Here, we report the identification of a novel …