Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade

S Nakao, Y Arai, M Tasaki, M Yamashita… - Science translational …, 2020 - science.org
The immune status of the tumor microenvironment is a key indicator in determining the
antitumor effectiveness of immunotherapies. Data support the role of activation and …

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade.

S Nakao, Y Arai, M Tasaki… - Science …, 2020 - search.ebscohost.com
A virus with benefits: Oncolytic viruses, which kill cancer cells, have received increasing
attention in recent years as the field has advanced toward biological and immune-based …

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade.

S Nakao, Y Arai, M Tasaki, M Yamashita… - Science Translational …, 2020 - europepmc.org
The immune status of the tumor microenvironment is a key indicator in determining the
antitumor effectiveness of immunotherapies. Data support the role of activation and …

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade

S Nakao, Y Arai, M Tasaki… - Science …, 2020 - pubmed.ncbi.nlm.nih.gov
The immune status of the tumor microenvironment is a key indicator in determining the
antitumor effectiveness of immunotherapies. Data support the role of activation and …