Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

GA Kinberger, TP Prakash, J Yu, G Vasquez… - Bioorganic & Medicinal …, 2016 - Elsevier
Antisense oligonucleotides (ASOs) conjugated to trivalent GalNAc ligands show 10-fold
enhanced potency for suppressing gene targets expressed in hepatocytes. Trivalent GalNAc …
被引用次数：50 相关文章

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

GA Kinberger, TP Prakash, J Yu… - Bioorganic & …, 2016 - pubmed.ncbi.nlm.nih.gov
Antisense oligonucleotides (ASOs) conjugated to trivalent GalNAc ligands show 10-fold
enhanced potency for suppressing gene targets expressed in hepatocytes. Trivalent GalNAc …

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

GA Kinberger, TP Prakash, J Yu, G Vasquez… - Bioorganic & Medicinal …, 2016 - infona.pl
Antisense oligonucleotides (ASOs) conjugated to trivalent GalNAc ligands show 10-fold
enhanced potency for suppressing gene targets expressed in hepatocytes. Trivalent GalNAc …
[PDF] academia.edu

[PDF][PDF] Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

GA Kinberger, TP Prakash, J Yu, G Vasquez… - receptor …, 2016 - academia.edu
abstract Antisense oligonucleotides (ASOs) conjugated to trivalent GalNAc ligands show 10-
fold enhanced potency for suppressing gene targets expressed in hepatocytes. Trivalent …

[引用][C] Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

GA Kinberger, TP Prakash, J Yu, G Vasquez… - Bioorganic & Medicinal …, 2016 - cir.nii.ac.jp
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense
oligonucleotides via ASGR mediated delivery to hepatocytes | CiNii Research CiNii 国立情報学 …

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes.

GA Kinberger, TP Prakash, J Yu… - Bioorganic & …, 2016 - europepmc.org
Antisense oligonucleotides (ASOs) conjugated to trivalent GalNAc ligands show 10-fold
enhanced potency for suppressing gene targets expressed in hepatocytes. Trivalent GalNAc …