A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka… - Proceedings of the …, 2021 - National Acad Sciences
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
M Mahoney, VC Damalanka, MA Tartell, DH Chung… - 2021 - cabidigitallibrary.org
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka… - Proceedings of the …, 2021 - ui.adsabs.harvard.edu
MM3122 represents an advanced lead candidate for clinical development as a novel
antiviral drug for COVID-19. In addition to being novel drugs, these selective TMRSS2 …
antiviral drug for COVID-19. In addition to being novel drugs, these selective TMRSS2 …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka, MA Tartell… - Proceedings of the …, 2021 - profiles.wustl.edu
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka, MA Tartell, DH Chung… - bioRxiv, 2021 - biorxiv.org
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of Severe Acute Respiratory Syndrome …
discovery. This protease activates the Spike protein of Severe Acute Respiratory Syndrome …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
M Mahoney, VC Damalanka, MA Tartell… - Proceedings of the …, 2021 - escholarship.org
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka… - Proceedings of the …, 2021 - pubmed.ncbi.nlm.nih.gov
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka, MA Tartell… - 2021 - digitalcommons.wustl.edu
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
[PDF][PDF] A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka, MA Tartell, D hee Chung… - scienceopen.com
1. Single point inhibition data using recombinant protease domain/FRET substrate for 4-
6.[Figure S1] 2. Protease selectivity data for 1 (ZFH7116) and 2 (VD2173).[Tables S1 and …
6.[Figure S1] 2. Protease selectivity data for 1 (ZFH7116) and 2 (VD2173).[Tables S1 and …
[HTML][HTML] A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
M Mahoney, VC Damalanka, MA Tartell… - Proceedings of the …, 2021 - ncbi.nlm.nih.gov
The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …
discovery. This protease activates the Spike protein of severe acute respiratory syndrome …