Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
The multifunctional nature of Alzheimer's disease calls for MTDLs (multitarget-directed
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F Nachon, E Carletti, C Ronco, M Trovaslet… - Biochemical …, 2013 - hal.science
The multifunctional nature of Alzheimer's disease calls for MTDLs (multitarget-directed
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F Nachon, E Carletti, C Ronco… - The Biochemical …, 2013 - pubmed.ncbi.nlm.nih.gov
The multifunctional nature of Alzheimer's disease calls for MTDLs (multitarget-directed
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F NACHON, E CARLETTI, C RONCO… - Biochemical …, 2013 - search.ebscohost.com
The multifunctional nature of Alzheimer's disease calls for MTDLs (multitarget-directed
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F Nachon, E Carletti, C Ronco, M Trovaslet… - The Biochemical …, 2013 - europepmc.org
The multifunctional nature of Alzheimer's disease calls for MTDLs (multitarget-directed
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
ligands) to act on different components of the pathology, like the cholinergic dysfunction and …
[PDF][PDF] Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F NACHON, E CARLETTI, C RONCO… - Biochem. J, 2013 - researchgate.net
(Trp82), and hydrogen bonding with the main chain carbonyl of the catalytic histidine
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
[PDF][PDF] Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F NACHON, E CARLETTI, C RONCO, M TROVASLET… - Biochem. J, 2013 - academia.edu
(Trp82), and hydrogen bonding with the main chain carbonyl of the catalytic histidine
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
[PDF][PDF] Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F NACHON, E CARLETTI, C RONCO… - Biochem. J, 2013 - researchgate.net
(Trp82), and hydrogen bonding with the main chain carbonyl of the catalytic histidine
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
[PDF][PDF] Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl …
F NACHON, E CARLETTI, C RONCO, M TROVASLET… - Biochem. J, 2013 - academia.edu
(Trp82), and hydrogen bonding with the main chain carbonyl of the catalytic histidine
residue. Huprine W forms additional interactions with hAChE, which explains its superior …
residue. Huprine W forms additional interactions with hAChE, which explains its superior …