Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure–activity relationships and discovery strategies to mitigate drug–drug interaction risks

STM Orr, SL Ripp, TE Ballard… - Journal of medicinal …, 2012 - ACS Publications
1. INTRODUCTION Cytochrome P450s (CYPs) constitute a superfamily of hemecontaining
enzymes that catalyze the oxidative metabolism of structurally diverse molecules including …
被引用次数：214 相关文章

[引用][C] Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction …

STM Orr, SL Ripp, TE Ballard… - Journal of …, 2012 - pubmed.ncbi.nlm.nih.gov
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity
relationships and discovery strategies to mitigate drug-drug interaction risks Mechanism-based …

[引用][C] Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction …

ST Orr, SL Ripp, TE Ballard, JL Henderson… - Journal of Medicinal …, 2012 - europepmc.org
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity
relationships and discovery strategies to mitigate drug-drug interaction risks. - Abstract - Europe …

[引用][C] Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug …

STM Orr, SL Ripp, TE Ballard, JL Henderson… - Journal of Medicinal …, 2012 - cir.nii.ac.jp
Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity
Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks | CiNii …