Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced …

X Han, L Zhao, W Xiang, B Miao, C Qin… - Journal of Medicinal …, 2023 - ACS Publications
We report the discovery of ARD-2051 as a potent and orally efficacious androgen receptor
(AR) proteolysis-targeting chimera degrader. ARD-2051 achieves DC50 values of 0.6 nM …
被引用次数：15 相关文章

Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced …

X Han, L Zhao, W Xiang, B Miao, C Qin, M Wang, T Xu… - 2023 - deepblue.lib.umich.edu
We report the discovery of ARD-2051 as a potent and orally efficacious androgen receptor
(AR) proteolysis-targeting chimera degrader. ARD-2051 achieves DC50 values of 0.6 nM …

Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced …

X Han, L Zhao, W Xiang, B Miao… - Journal of …, 2023 - pubmed.ncbi.nlm.nih.gov
We report the discovery of ARD-2051 as a potent and orally efficacious androgen receptor
(AR) proteolysis-targeting chimera degrader. ARD-2051 achieves DC 50 values of 0.6 nM …