[HTML][HTML] Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.
TE Park, N Mustafaoglu, A Herland… - Nature …, 2019 - europepmc.org
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland, R Hasselkus… - Nature …, 2019 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p> The high selectivity of the human blood-brain
barrier (BBB) restricts delivery of many pharmaceuticals and therapeutic antibodies to the …
barrier (BBB) restricts delivery of many pharmaceuticals and therapeutic antibodies to the …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland… - Nature …, 2019 - pubmed.ncbi.nlm.nih.gov
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.
TE Park, N Mustafaoglu, A Herland… - Nature …, 2019 - search.ebscohost.com
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland… - Nature …, 2019 - scholarship.miami.edu
Abstract Antibodies-pharmacology Astrocytes Blood-Brain Barrier-cytology Blood-Brain
Barrier-metabolism Drug Delivery Systems-methods Drug Evaluation, Preclinical …
Barrier-metabolism Drug Delivery Systems-methods Drug Evaluation, Preclinical …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function, drug penetration, and antibody shuttling properties
TE Park, N Mustafaoglu, A Herland, R Hasselkus… - bioRxiv, 2018 - biorxiv.org
The highly specialized human brain microvascular endothelium forms a selective blood-
brain barrier (BBB) with adjacent pericytes and astrocytes that restricts delivery of many …
brain barrier (BBB) with adjacent pericytes and astrocytes that restricts delivery of many …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland, R Hasselkus… - 2019 - scholarworks.unist.ac.kr
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
[PDF][PDF] Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland, R Hasselkus… - core.ac.uk
Results Developmentally inspired differentiation of brain endothelium. Given that the BBB
first forms in the developing brain in a relatively oxygen-poor environment (1–8%) before …
first forms in the developing brain in a relatively oxygen-poor environment (1–8%) before …
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland… - Nature …, 2019 - ui.adsabs.harvard.edu
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …
pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we …