Muvalaplin, an oral small molecule inhibitor of lipoprotein (a) formation: a randomized clinical trial

SJ Nicholls, SE Nissen, C Fleming, S Urva, J Suico… - Jama, 2023 - jamanetwork.com
Importance Lipoprotein (a)(Lp [a]) is associated with atherosclerotic disease and aortic
stenosis. Lp (a) forms by bonding between apolipoprotein (a)(apo [a]) and apo B 100 …

Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein (a) Formation: A Randomized Clinical Trial.

SJ Nicholls, SE Nissen, C Fleming… - JAMA: Journal of …, 2023 - search.ebscohost.com
Abstract Key Points: Question: Can muvalaplin, an orally administered small molecule
inhibitor of lipoprotein (a)(Lp [a]) formation, achieve safe and tolerable plasma …

[HTML][HTML] Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein (a) Formation: A Randomized Clinical Trial

SJ Nicholls, SE Nissen, C Fleming, S Urva, J Suico… - JAMA, 2023 - ncbi.nlm.nih.gov
Interventions The single ascending dose treatment evaluated the effect of a single dose of
muvalaplin ranging from 1 mg to 800 mg or placebo taken by healthy participants with any …

Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein (a) Formation: A Randomized Clinical Trial

SJ Nicholls, SE Nissen, C Fleming, S Urva… - …, 2023 - pubmed.ncbi.nlm.nih.gov
Importance Lipoprotein (a)(Lp [a]) is associated with atherosclerotic disease and aortic
stenosis. Lp (a) forms by bonding between apolipoprotein (a)(apo [a]) and apo B100 …

Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein (a) Formation: A Randomized Clinical Trial.

SJ Nicholls, SE Nissen, C Fleming, S Urva, J Suico… - JAMA, 2023 - europepmc.org
Interventions The single ascending dose treatment evaluated the effect of a single dose of
muvalaplin ranging from 1 mg to 800 mg or placebo taken by healthy participants with any …

Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein (a) Formation: A Randomized Clinical Trial.

SJ Nicholls, SE Nissen, C Fleming, S Urva, J Suico… - JAMA, 2023 - europepmc.org
Interventions The single ascending dose treatment evaluated the effect of a single dose of
muvalaplin ranging from 1 mg to 800 mg or placebo taken by healthy participants with any …