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Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiu, Z Glass, J Chen, M Haas, X Jin… - Proceedings of the …, 2021 - National Acad Sciences
Loss-of-function mutations in Angiopoietin-like 3 (Angptl3) are associated with lowered
blood lipid levels, making Angptl3 an attractive therapeutic target for the treatment of human …
被引用次数：276 相关文章

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiu, Z Glass, J Chen, M Haas… - Proceedings of the …, 2021 - pubmed.ncbi.nlm.nih.gov
Loss-of-function mutations in Angiopoietin-like 3 (Angptl3) are associated with lowered
blood lipid levels, making Angptl3 an attractive therapeutic target for the treatment of human …

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiu, Z Glass, J Chen, M Haas, X Jin… - Proceedings of the …, 2021 - ui.adsabs.harvard.edu
Genome editing technologies enable the permanent repair of disease-causing genetic
mutations. However, the application of this technology has been limited by the technical …

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing ofAngptl3

M Qiu, Z Glass, J Chen, M Haas, X Jin, X Zhao… - Proceedings of the …, 2021 - cir.nii.ac.jp
抄録< jats: title> Significance</jats: title>< jats: p> Genome editing technologies enable the
permanent repair of disease-causing genetic mutations. However, the application of this …

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiu, Z Glass, J Chen, M Haas, X Jin, X Zhao… - Proceedings of the …, 2021 - JSTOR
Loss-of-function mutations in Angiopoietin-like 3 (Angptl3) are associated with lowered
blood lipid levels, making Angptl3 an attractive therapeutic target for the treatment of human …

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3.

M Qiu, Z Glass, J Chen, M Haas, X Jin… - Proceedings of the …, 2021 - europepmc.org
Results In Vivo Screening of LNPs for mRNA Delivery. The tail-branched bioreducible
lipidoids were prepared via a combinatory solvent free Michael addition reaction between …
[HTML] nih.gov

[HTML][HTML] Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiu, Z Glass, J Chen, M Haas, X Jin… - Proceedings of the …, 2021 - ncbi.nlm.nih.gov
Results In Vivo Screening of LNPs for mRNA Delivery. The tail-branched bioreducible
lipidoids were prepared via a combinatory solvent free Michael addition reaction between …

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiu, Z Glass, J Chen, M Haas, X Jin, X Zhao, X Rui… - 2021 - dspace.mit.edu
Loss-of-function mutations in Angiopoietin-like 3 (Angptl3) are associated with lowered
blood lipid levels, making Angptl3 an attractive therapeutic target for the treatment of human …
[PDF] researchgate.net

[PDF][PDF] Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

M Qiua, Z Glassa, J Chena, M Haasb, X Jinb, X Zhaoa… - PNAS, 2021 - researchgate.net
Results In Vivo Screening of LNPs for mRNA Delivery. The tail-branched bioreducible
lipidoids were prepared via a combinatory solvent free Michael addition reaction between …