Attention bias toward threat is associated with exaggerated fear expression and impaired extinction in PTSD
BackgroundPost-traumatic stress disorder (PTSD) develops in a minority of traumatized
individuals. Attention biases to threat and abnormalities in fear learning and extinction are …
individuals. Attention biases to threat and abnormalities in fear learning and extinction are …
Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity
SD Norrholm, T Jovanovic, IW Olin, LA Sands… - Biological …, 2011 - Elsevier
BACKGROUND:: The symptoms of posttraumatic stress disorder (PTSD) can be explained,
at least in part, as an inability to inhibit learned fear during conditions of safety. Our group …
at least in part, as an inability to inhibit learned fear during conditions of safety. Our group …
Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures
EM Glover, JE Phifer, DF Crain… - Depression and …, 2011 - Wiley Online Library
Background: Posttraumatic stress disorder (PTSD) patients show heightened fear responses
to trauma reminders and an inability to inhibit fear in the presence of safety reminders. Brain …
to trauma reminders and an inability to inhibit fear in the presence of safety reminders. Brain …
[HTML][HTML] PTSD symptom severity is associated with increased recruitment of top-down attentional control in a trauma-exposed sample
Background Recent neuroimaging work suggests that increased amygdala responses to
emotional stimuli and dysfunction within regions mediating top down attentional control …
emotional stimuli and dysfunction within regions mediating top down attentional control …
The innate alarm system in PTSD: conscious and subconscious processing of threat
Highlights•Subconscious processing of threat is an understudied, yet key, process in
PTSD.•The innate alarm system is central to responding to threat subconsciously.•The …
PTSD.•The innate alarm system is central to responding to threat subconsciously.•The …
Neural correlates of attention bias to threat in post-traumatic stress disorder
Attentional biases have been proposed to contribute to symptom maintenance in
posttraumatic stress disorder (PTSD), although the neural correlates of these processes …
posttraumatic stress disorder (PTSD), although the neural correlates of these processes …
[HTML][HTML] Avoidant symptoms in PTSD predict fear circuit activation during multimodal fear extinction
Convergent evidence suggests that individuals with posttraumatic stress disorder (PTSD)
exhibit exaggerated avoidance behaviors as well as abnormalities in Pavlonian fear …
exhibit exaggerated avoidance behaviors as well as abnormalities in Pavlonian fear …
The centrality of fear extinction in linking risk factors to PTSD: A narrative review
Recent prospective studies in emergency services have identified impaired fear extinction
learning and memory to be a significant predictor of Posttraumatic Stress Disorder (PTSD) …
learning and memory to be a significant predictor of Posttraumatic Stress Disorder (PTSD) …
Altered processing of contextual information during fear extinction in PTSD: an fMRI study
A RougemontBücking, C Linnman… - CNS neuroscience & …, 2011 - Wiley Online Library
Medial prefrontal cortical areas have been hypothesized to underlie altered contextual
processing in posttraumatic stress disorder (PTSD). We investigated brain signaling of …
processing in posttraumatic stress disorder (PTSD). We investigated brain signaling of …
[HTML][HTML] Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder
Fear conditioning is an established model for investigating posttraumatic stress disorder
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event …
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event …