Clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis—a meta-analysis of comparative and non-comparative clinical trials

J Zwang, PL Olliaro - PLoS neglected tropical diseases, 2014 - journals.plos.org
Background Extensive use of praziquantel for treatment and control of schistosomiasis
requires a comprehensive understanding of efficacy and safety of various doses for different …

A multicentre randomized controlled trial of the efficacy and safety of single-dose praziquantel at 40 mg/kg vs. 60 mg/kg for treating intestinal schistosomiasis in the …

PL Olliaro, MT Vaillant, VJ Belizario… - PLoS neglected …, 2011 - journals.plos.org
Background Praziquantel at 40 mg/kg in a single dose is the WHO recommended treatment
for all forms of schistosomiasis, but 60 mg/kg is also deployed nationally …

Efficacy of Praziquantel for the Treatment of Human Schistosomiasis in Ethiopia: A Systematic Review and MetaAnalysis

T Hailegebriel, E Nibret… - Journal of Tropical …, 2021 - Wiley Online Library
Background. Schistosomiasis is one of the neglected tropical diseases causing a serious
human health problem in Ethiopia. Praziquantel is the only drug that has been used for the …

Utility of repeated praziquantel dosing in the treatment of schistosomiasis in high-risk communities in Africa: a systematic review

CH King, SK Olbrych, M Soon, ME Singer… - PLoS neglected …, 2011 - journals.plos.org
Background Controversy persists about the optimal approach to drug-based control of
schistosomiasis in high-risk communities. In a systematic review of published studies, we …

Use of praziquantel against schistosomiasis: a review of current status

V Kumar, B Gryseels - International journal of antimicrobial agents, 1994 - Elsevier
Praziquantel therapy has become an important component of any programme directed
towards schistosomiasis control. This disease being prevalent in many disadvantaged …

Efficacy of praziquantel treatment regimens in pre-school and school aged children infected with schistosomiasis in sub-Saharan Africa: a systematic review

M Kabuyaya, MJ Chimbari, S Mukaratirwa - Infectious diseases of poverty, 2018 - Springer
Background Schistosomiasis is a serious public health burden in sub-Saharan Africa.
Praziquantel is the only drug recommended by the World Health Organization to treat both …

Efficacy and side effects of praziquantel against Schistosoma mansoni in a community of western Côte d'Ivoire

G Raso, EK N'Goran, A Toty, A Luginbühl… - Transactions of the …, 2004 - academic.oup.com
Praziquantel is efficacious against the adult stages of all human schistosome parasites, and
has become the drug of choice for morbidity control of schistosomiasis. There is concern that …

Praziquantel efficacy and longterm appraisal of schistosomiasis control in Pemba Island

A Guidi, C Andolina, S Makame Ame… - Tropical Medicine & …, 2010 - Wiley Online Library
Objective To determine whether praziquantel (PZQ) has retained its efficacy against
Schistosoma haematobium on Pemba Island after 20 years of mass administrationalbeit …

Praziquantel, Mefloquine-Praziquantel, and Mefloquine-Artesunate-Praziquantel against Schistosoma haematobium: A Randomized, Exploratory, Open-Label Trial

J Keiser, KD Silué, LK Adiossan… - PLoS neglected …, 2014 - journals.plos.org
Background Treatment and morbidity control of schistosomiasis relies on a single drug,
praziquantel. Hence, there is a pressing need to develop additional therapeutics against …

Efficacy and side effects of praziquantel in the treatment of Schistosomiasis mansoni in schoolchildren in Shesha Kekele Elementary School, Wondo Genet, Southern …

B Erko, A Degarege, K Tadesse, A Mathiwos… - Asian Pacific journal of …, 2012 - Elsevier
Objective To evaluate the efficacy and side effects of praziquantel (PZQ) in the treatment of
schistosomiasis in Ethiopia. Methods In a cross-sectional study, stool specimens were …