Objective It is a widely held belief that affective disorders are progressive of nature; however,
some recent reviews have questioned this belief. The objective of the present systematic …

Findings from several studies have suggested that the risk of recurrence increases with the
number of previous episodes in depressive and bipolar disorders. However, a …

BackgroundIt is in dispute whether affective relapse disrupts psychosocial functioning to the
same extent in depressed and manic patients. MethodA prospective, naturalistic …

Objective: It is generally accepted that one of the most important predictors of recurrence in
depressive and bipolar disorders is the number of previous episodes. However, very few …

Objective: As npart of the National Institute of Mental Health Collaborative Study of the
Psychobiology of Depression, the comparative course of manic depressive (bipolar) and …

Context The phenomenology of bipolar I disorder affects treatment and prognosis. Objective
To describe the duration of bipolar I mood episodes and factors associated with recovery …

Background: The risk of recurrence in affective disorder is affected by socio-demographic
variables such as gender, age at onset and marital status and by illness related factors as …

Objectives The longterm outcome of bipolar disorder (BD) has been extensively
investigated. However, previous studies may be biased towards hospitalized patients with …

Objective Characteristics of initial illness in bipolar disorder (BD) may predict later morbidity.
Method We reviewed computerized clinical records and life charts of DSMIVTR BDI or …

Rosa AR, GonzálezOrtega I, GonzálezPinto A, Echeburúa E, Comes M, MartínezÀran A,
Ugarte A, Fernández M, Vieta E. Oneyear psychosocial functioning in patients in the early …