Effect of probiotic supplementation on seizure activity and cognitive performance in PTZ-induced chemical kindling

S Bagheri, A Heydari, A Alinaghipour, M Salami - Epilepsy & Behavior, 2019 - Elsevier
Epilepsy is one of the most common neurological disorders that severely affect life quality of
many people worldwide. Ion transport in the neuronal membrane, inhibitory–excitatory …

Effects of probiotics on GABA/glutamate and oxidative stress in PTZ-induced acute seizure model in rats

AC Ciltas, CE Toy, H Güneş, M Yaprak - Epilepsy Research, 2023 - Elsevier
Studies conducted in recent years have indicated a relationship between epilepsy and gut
microbiota. Ion channels, excitatory/inhibitory balance and regulatory systems play a role in …

Probiotics and Nigella sativa extract supplementation improved behavioral and electrophysiological effects of PTZ-induced chemical kindling in rats

S Tahmasebi, S Oryan, HR Mohajerani, N Akbari… - Epilepsy & Behavior, 2020 - Elsevier
Introduction Epilepsy is a most common neurological disorder that has negative effects on
cognition. In the present study, we investigated the protective effect of Nigella sativa (NS) …

Protective effects of long-term probiotic mixture supplementation against pentylenetetrazole-induced seizures, inflammation and oxidative stress in rats

E Kilinc, S Ankarali, D Ayhan, H Ankarali… - The Journal of nutritional …, 2021 - Elsevier
Emerging evidence indicates that dysbiosis of gut microbiota plays an important role in
epilepsy, although the underlying mechanisms remain unclear due to the complex nature of …

[HTML][HTML] Evidences for a role of gut microbiota in pathogenesis and management of epilepsy

J Amlerova, J Šroubek, F Angelucci, J Hort - International Journal of …, 2021 - mdpi.com
Epilepsy as a chronic neurological disorder is characterized by recurrent, unprovoked
epileptic seizures. In about half of the people who suffer from epilepsy, the root cause of the …

[HTML][HTML] Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing

X Gong, L Liu, X Li, J Xiong, J Xu, D Mao, L Liu - Frontiers in Nutrition, 2022 - frontiersin.org
Aims Epilepsy is a neurological disease occurring worldwide. Alterations in the gut microbial
composition may be involved in the development of Epilepsy. The study aimed to investigate …

Gut microbiota and epilepsy: a systematic review on their relationship and possible therapeutics

A Arulsamy, QY Tan, V Balasubramaniam… - ACS Chemical …, 2020 - ACS Publications
Dysbiosis of gut microbiota may lead to a range of diseases including neurological
disorders. Thus, it is hypothesized that regulation of the intestinal microbiota may prevent or …

The beneficial effect of probiotics as a supplementary treatment in drug-resistant epilepsy: a pilot study

M Gómez-Eguílaz, JL Ramón-Trapero… - Beneficial …, 2018 - brill.com
Epilepsy is a neurological disease with high global prevalence. Despite the range of drug-
based treatments currently available to control the condition, one in 3 patients experiences …

First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat

R Citraro, F Lembo, C De Caro, M Tallarico… - …, 2021 - Wiley Online Library
Objective A large number of studies have highlighted the important role of the gut microbiota
in the pathophysiology of neurological disorders, suggesting that its manipulation might …

[HTML][HTML] Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic …

M Dahlin, SS Singleton, JA David, A Basuchoudhary… - …, 2022 - thelancet.com
Background Recently, studies have suggested a role for the gut microbiota in epilepsy. Gut
microbial changes during ketogenic diet (KD) treatment of drug-resistant epilepsy have been …