Assessment of the Efficacy of Bone MarrowDerived Mesenchymal Stem Cells against a MonoiodoacetateInduced Osteoarthritis Model in Wistar Rats
Osteoarthritis (OA) of the knee is a debilitating condition that can severely limit an
individual's mobility and quality of life. This study was designed to evaluate the efficacy of …
individual's mobility and quality of life. This study was designed to evaluate the efficacy of …
Mesenchymal stem cells reduce pain but not degenerative changes in a monoiodoacetate rat model of osteoarthritis
GM van Buul, M Siebelt, MJC Leijs… - Journal of …, 2014 - Wiley Online Library
We studied the effects of intraarticularly injected bone marrow derived mesenchymal stem
cells (MSCs), as well as freshly isolated bone marrow mononuclear cells (BMMNCs), on …
cells (MSCs), as well as freshly isolated bone marrow mononuclear cells (BMMNCs), on …
[HTML][HTML] Ameliorative effects of undifferentiated and differentiated BM-MSCs in MIA-induced osteoarthritic Wistar rats: roles of NF-κB and MMPs signaling pathways
AS Saleh, M Abdel-Gabbar, H Gabr… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objectives: Osteoarthritis (OA) is a degenerative joint condition that is persistent. OA affects
millions of people throughout the world. Both people and society are heavily economically …
millions of people throughout the world. Both people and society are heavily economically …
[HTML][HTML] Mesenchymal stem cell therapy in a rat model of osteoarthritis
GM Van Buul, M Siebelt, MJ Leijs, P Bos… - Osteoarthritis and …, 2012 - oarsijournal.com
Purpose: Mesenchymal stem cells (MSCs) are promising candidates for cartilage
regeneration and osteoarthritis (OA) therapies, due to their ability to form cartilage and to …
regeneration and osteoarthritis (OA) therapies, due to their ability to form cartilage and to …
[HTML][HTML] The effect of intra-articular versus intravenous injection of mesenchymal stem cells on experimentally-Induced knee joint osteoarthritis
A Mostafa, HE Korayem, E Fekry… - Journal of Microscopy …, 2021 - journals.lww.com
Background: Osteoarthritis (OA) is a chronic degenerative debilitating disease, primarily
affects joints, particularly weight-bearing areas. The surface layer of the articular cartilage …
affects joints, particularly weight-bearing areas. The surface layer of the articular cartilage …
[HTML][HTML] Anti-inflammatory and anti-oxidant activities of mesenchymal stem cells in chemically induced arthritic rats
MY Zaky, EE Mohamed, R Mahmoud… - Molecular Biology …, 2023 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been extensively used as cell-
based treatments for decades due to their anti-inflammatory, immunomodulatory, and …
based treatments for decades due to their anti-inflammatory, immunomodulatory, and …
Combinatory Effects of Bone MarrowDerived Mesenchymal Stem Cells and Indomethacin on AdjuvantInduced Arthritis in Wistar Rats: Roles of IL1β, IL4, Nrf2 …
Rheumatoid arthritis (RA) is a disorder triggered by autoimmune reactions and related with
chronic inflammation and severe disability. Bone Marrowderived Mesenchymal Stem Cells …
chronic inflammation and severe disability. Bone Marrowderived Mesenchymal Stem Cells …
Potency of Bone MarrowDerived Mesenchymal Stem Cells and Indomethacin in Complete Freund's AdjuvantInduced Arthritic Rats: Roles of TNFα, IL10, iNOS, MMP9, and …
Rheumatoid arthritis (RA) is an autoimmune syndrome affecting joint spaces, leading to the
disabled state. Currently, there is no optimal therapy for RA except for systemic …
disabled state. Currently, there is no optimal therapy for RA except for systemic …
Multiple intra-articular injections of allogeneic bone marrow-derived stem cells potentially improve knee lesions resulting from surgically induced osteoarthritis: an …
EE Mahmoud, N Adachi, AS Mawas… - The bone & joint …, 2019 - boneandjoint.org.uk
Aim Mesenchymal stem cells (MSCs) have several properties that may support their use as
an early treatment option for osteoarthritis (OA). This study investigated the role of multiple …
an early treatment option for osteoarthritis (OA). This study investigated the role of multiple …
Treatment of collagen-induced arthritis using immune modulatory properties of human mesenchymal stem cells
KH Park, CH Mun, MI Kang, SW Lee… - Cell …, 2016 - journals.sagepub.com
Mesenchymal stem cells (MSCs) have immune modulatory properties. We investigated the
potential therapeutic effects of human bone marrow (BM)-, adipose tissue (AD)-, and cord …
potential therapeutic effects of human bone marrow (BM)-, adipose tissue (AD)-, and cord …
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