Helminth infections are responsible for a considerable public health burden, yet the current
drug armamentarium is small. Given the high cost of drug discovery and development, the …

Parasitic worms (helminths) have accompanied humans for thousands of years and, still
today, they are pervasive where poverty persists, including large parts of Southeast Asia and …

More than 2 billion people are infected with helminth parasites across the globe. The
burgeoning drug resistance against current anthelmintics in parasitic worms of humans and …

Control of helminth parasites is a key challenge for human and veterinary medicine. In the
absence of effective vaccines and adequate sanitation, prophylaxis and treatment commonly …

Helminth infections are an important constraint on the health and development of poor
children and adults. Anthelmintic treatment programmes provide a safe and effective …

Schistosomiasis is a major neglected tropical disease. Control of schistosomiasis currently
relies on a single drug, praziquantel, and despite its efficacy against the all schistosome …

The last half-century has provided all of the (few) drugs currently used to treat human
helminthiases. Concern regarding the long-term utility of these drugs, given how readily …

Parasitic diseases have an enormous health, social and economic impact and are a
particular problem in tropical regions of the world. Diseases caused by protozoa and …

Background: In the first decade of the 21st century, worm infections are still very common,
especially–but not exclusively–in the developing world. Objective: To review the current …

Expansion of MDA programs to attain elimination of human helminthiases is a noble and
worthwhile endeavor. Increased drug pressure should be expected to select resistance …