Circulating tumor DNA for prognosis assessment and postoperative management after curativeintent resection of colorectal liver metastases
T Reinert, LMS Petersen, TV Henriksen… - … journal of cancer, 2022 - Wiley Online Library
The recurrence rate of colorectal liver metastases (CRLM) patients treated with curative
intent is above 50%. Standard of care surveillance includes intensive computed …
intent is above 50%. Standard of care surveillance includes intensive computed …
Circulating tumor DNA as a marker of minimal residual disease after radical resection of colorectal liver metastases
F Marmorino, M Prisciandaro, M Giordano… - JCO precision …, 2022 - ascopubs.org
PURPOSE Prognostic tools to estimate the risk of relapse for patients with liver-limited
metastatic colorectal cancer (LL-mCRC) undergoing resection with curative intent are …
metastatic colorectal cancer (LL-mCRC) undergoing resection with curative intent are …
[HTML][HTML] Tumour-agnostic circulating tumour DNA analysis for improved recurrence surveillance after resection of colorectal liver metastases: A prospective cohort …
N Øgaard, T Reinert, TV Henriksen… - European Journal of …, 2022 - Elsevier
Purpose Nearly 50% of patients recur within two years after curatively intended resection of
colorectal cancer liver metastasis (CRLM). The optimal surveillance strategy is unknown due …
colorectal cancer liver metastasis (CRLM). The optimal surveillance strategy is unknown due …
Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study
Background In patients with resectable colorectal liver metastases (CRLM), the role of pre-
and postoperative systemic therapy continues to be debated. Previous studies have shown …
and postoperative systemic therapy continues to be debated. Previous studies have shown …
Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases
K Bolhuis, I van't Erve, C Mijnals… - …, 2021 - thelancet.com
Background Recurrence rates after resection of colorectal cancer liver metastases (CRLM)
are high and correlate with worse survival. Postoperative circulating tumour DNA (ctDNA) is …
are high and correlate with worse survival. Postoperative circulating tumour DNA (ctDNA) is …
Serial circulating tumor DNA (ctDNA) and recurrence risk in patients (pts) with resectable colorectal liver metastasis (CLM).
J Tie, Y Wang, S Springer, I Kinde, HL Wong… - 2016 - ascopubs.org
e15131 Background: In pts with metastatic colorectal cancer (mCRC), the resection of
isolated CLM is potentially curative. Previous studies have shown that ctDNA can be …
isolated CLM is potentially curative. Previous studies have shown that ctDNA can be …
Circulating Tumour DNA as Biomarker for Colorectal Liver Metastases: A Systematic Review and Meta-Analysis
L Wullaert, JM van Rees, JWM Martens, HMW Verheul… - Cells, 2023 - mdpi.com
Circulating tumour DNA (ctDNA) is a potential biomarker that could contribute to more
judicious patient selection for personalised treatment. This review and meta-analysis gives …
judicious patient selection for personalised treatment. This review and meta-analysis gives …
Impact of preoperative circulating tumor DNA status on survival outcomes after hepatectomy for resectable colorectal liver metastases
S Kobayashi, Y Nakamura, H Taniguchi… - Annals of Surgical …, 2021 - Springer
Background The optimal perioperative management of patients who undergo hepatectomy
for resectable colorectal liver metastases (CRLM) remains unclear due to the lack of reliable …
for resectable colorectal liver metastases (CRLM) remains unclear due to the lack of reliable …
Perioperative circulating tumor DNA in colorectal liver metastases: concordance with metastatic tissue and predictive value for tumor burden and prognosis
Y He, X Ma, K Chen, F Liu, S Cai… - Cancer management …, 2020 - Taylor & Francis
Background The surgical resection of colorectal cancer with liver metastases (CLM) has
proven to be the most important modality for long-term survival, while effective biomarkers …
proven to be the most important modality for long-term survival, while effective biomarkers …
Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies
Studies in multiple solid tumor types have demonstrated the prognostic significance of
ctDNA analysis after curative intent surgery. A combined analysis of data across completed …
ctDNA analysis after curative intent surgery. A combined analysis of data across completed …
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