[HTML][HTML] Chinese expert consensus on conversion therapy for hepatocellular carcinoma (2021 edition)

HC Sun, J Zhou, Z Wang, X Liu, Q Xie… - … surgery and nutrition, 2022 - ncbi.nlm.nih.gov
Recent advances in systemic and locoregional treatments for patients with unresectable or
advanced hepatocellular carcinoma (HCC) have resulted in improved response rates. This …

Downstaging conversion therapy in patients with initially unresectable advanced hepatocellular carcinoma: an overview

HC Sun, XD Zhu - Frontiers in oncology, 2021 - frontiersin.org
The high mortality rate associated with hepatocellular carcinoma (HCC) is partly due to the
high proportion of patients who present with advanced stage disease at diagnosis, for whom …

Conversion therapy and maintenance therapy for primary hepatocellular carcinoma

H Zhou, T Song - BioScience Trends, 2021 - jstage.jst.go.jp
The preferred treatment for hepatocellular carcinoma (HCC) is surgery, which is the only
way to achieve long-term survival and even a cure. However, the vast majority of patients …

[HTML][HTML] Chinese expert consensus on neoadjuvant and conversion therapies for hepatocellular carcinoma

HT Zhao, JQ Cai - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
The low resection and high recurrence rates in hepatocellular carcinoma (HCC) are the
major challenges to improving prognosis. Neoadjuvant and conversion therapies are …

Conversion therapy for initially unresectable hepatocellular carcinoma using a combination of toripalimab, lenvatinib plus TACE: real-world study

WF Qu, ZB Ding, XD Qu, Z Tang, GQ Zhu, XT Fu… - BJS open, 2022 - academic.oup.com
Background Combination conversion therapies afforded curative surgery chance for initially
unresectable hepatocellular carcinoma (uHCC). This study aimed to evaluate the …

[PDF][PDF] Downstaging hepatocellular carcinoma: a systematic review and pooled analysis

ND Parikh, AK Waljee, AG Singal - Liver transplantation, 2015 - Wiley Online Library
Downstaging can facilitate liver transplantation (LT) for patients outside of Milan criteria with
hepatocellular carcinoma (HCC); however, the optimal protocol and downstaging outcomes …

Surgical conversion for initially unresectable locally advanced hepatocellular carcinoma using a triple combination of angiogenesis inhibitors, anti-PD-1 antibodies …

J Zhang, X Zhang, H Mu, G Yu, W Xing, L Wang… - Frontiers in …, 2021 - frontiersin.org
Background Recent research has shown that selected patients with initially unresectable
hepatocellular carcinoma (HCC) are able to achieve conversion to resectable disease …

Conversion surgery after preoperative therapy for advanced hepatocellular carcinoma in the era of molecular targeted therapy and immune checkpoint inhibitors

J Arita, A Ichida, R Nagata, Y Mihara… - Journal of Hepato …, 2022 - Wiley Online Library
Background Optimal strategies for advanced hepatocellular carcinoma (HCC) tumors, such
as those with vascular tumor thrombus and those with extrahepatic metastases are unclear …

Recent advances in hepatocellular carcinoma treatment

ND Parikh, A Pillai - Clinical Gastroenterology and Hepatology, 2021 - cghjournal.org
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related morbidity and
mortality worldwide, largely as a result of 3 main factors:(1) competing risk of cirrhosis, which …

Evolving therapeutic landscape of advanced hepatocellular carcinoma

C Yang, H Zhang, L Zhang, AX Zhu… - Nature reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is one of the most common solid malignancies worldwide.
A large proportion of patients with HCC are diagnosed at advanced stages and are only …