Internalization kinetics and cytoplasmic localization of functionalized diatomite nanoparticles in cancer cells by Raman imaging

S Managò, N Migliaccio, M Terracciano… - Journal of …, 2018 - Wiley Online Library
Porous biosilica nanoparticles obtained from diatomites (DNPs) have been recently
demonstrated to be nontoxic nanovectors of therapeutic agents in cancer cells. In this work …

Surface bioengineering of diatomite based nanovectors for efficient intracellular uptake and drug delivery

M Terracciano, MA Shahbazi, A Correia, I Rea… - Nanoscale, 2015 - pubs.rsc.org
Diatomite is a natural porous silica material of sedimentary origin. Due to its peculiar
properties, it can be considered as a valid surrogate of synthetic porous silica for nano …

N-Doped graphene quantum dot@ mesoporous silica nanoparticles modified with hyaluronic acid for fluorescent imaging of tumor cells and drug delivery

W Gui, J Zhang, X Chen, D Yu, Q Ma - Microchimica Acta, 2018 - Springer
The authors describe new bifunctional mesoporous silica nanoparticles (NPs) for specific
targeting of tumor cells and for intracellular delivery of the cancer drug doxorubicin (DOX) …

Free-labeled nanoclay intracellular uptake tracking by confocal Raman imaging

N Iturrioz-Rodríguez, R Martín-Rodríguez… - Applied Surface …, 2021 - Elsevier
Laponite is a nanoplatform that has been successfully used as a new biomaterial for drug
delivery, tissue engineering and bioimaging at the nanoscale. In general, a deep knowledge …

A study of mesoporous silica-encapsulated gold nanorods as enhanced light scattering probes for cancer cell imaging

Q Zhan, J Qian, X Li, S He - Nanotechnology, 2009 - iopscience.iop.org
Mesoporous encapsulation of gold nanorods (GNRs) in a silica shell of controllable
thickness (4.5–25.5 nm) was realized through a single-step coating method without any …

Nanoparticle uptake and their co-localization with cell compartments–a confocal Raman microscopy study at single cell level

I Estrela-Lopis, G Romero, E Rojas… - Journal of Physics …, 2011 - iopscience.iop.org
Abstract Confocal Raman Microscopy, a non-invasive, non-destructive and label-free
technique, was employed to study the uptake and localization of nanoparticles (NPs) in the …

Cancer cell targeting and therapeutic delivery of silver nanoparticles by mesoporous silica nanocarriers: Insights into the action mechanisms using quantitative …

S Montalvo-Quiros, G Aragoneses-Cazorla… - Nanoscale, 2019 - pubs.rsc.org
An approach for safely delivering AgNPs to cancer cells and the evaluation of the affected
cellular mechanism are presented. The use of mesoporous silica nanoparticles (MSNs) as …

Mesoporous silica nanoparticles functionalized with fluorescent and MRI reporters for the visualization of murine tumors overexpressing α v β 3 receptors

H Hu, F Arena, E Gianolio, C Boffa, E Di Gregorio… - Nanoscale, 2016 - pubs.rsc.org
A novel fluorescein/Gd-DOTAGA containing nanoprobe for the visualization of tumors by
optical and Magnetic Resonance Imaging (MRI) is reported herein. It is based on the …

Hybrid nanoparticles for drug delivery and bioimaging: mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye

M Xie, H Shi, K Ma, H Shen, B Li, S Shen… - Journal of colloid and …, 2013 - Elsevier
The development of a drug delivery system with fluorescent biolabels is important in anti-
cancer drug delivery application due to the potential for simultaneous diagnosis and …

Development of non-porous silica nanoparticles towards cancer photo-theranostics

C Mochizuki, J Nakamura, M Nakamura - Biomedicines, 2021 - mdpi.com
Nanoparticles have demonstrated several advantages for biomedical applications, including
for the development of multifunctional agents as innovative medicine. Silica nanoparticles …