Aggressive and malignant prolactinomas
NC Olarescu, LG Perez-Rivas, F Gatto, T Cuny… - …, 2019 - karger.com
Prolactin-secreting tumors (prolactinomas) represent the most common pituitary tumor type,
accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and …
accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and …
Epidemiology and management challenges in prolactinomas
Clinically relevant pituitary adenomas are present in about 1 per 1,000 of the general
population and prolactinomas are by far the most common clinical subtype of pituitary …
population and prolactinomas are by far the most common clinical subtype of pituitary …
Pathogenesis of prolactinomas
A Spada, G Mantovani, A Lania - Pituitary, 2005 - Springer
In recent years the demonstration that human pituitary adenomas are monoclonal in origin
provides further evidence that pituitary neoplasia arise from the replication of a single …
provides further evidence that pituitary neoplasia arise from the replication of a single …
Treatment strategies for dopamine agonist-resistant and aggressive prolactinomas: a comprehensive analysis of the literature
Despite most of the prolactinomas can be treated with endocrine therapy and/or surgery, a
significant percentage of these tumors can be resistant to endocrine treatments and/or recur …
significant percentage of these tumors can be resistant to endocrine treatments and/or recur …
What are the markers of aggressiveness in prolactinomas? Changes in cell biology, extracellular matrix components, angiogenesis and genetics
A Gurlek, N Karavitaki, O Ansorge… - European Journal of …, 2007 - academic.oup.com
Prolactinoma is the most common pituitary tumour in adults. Macroprolactinomas,
particularly in men, may occasionally exhibit a very aggressive clinical course as evidenced …
particularly in men, may occasionally exhibit a very aggressive clinical course as evidenced …
Aggressive and malignant prolactin pituitary tumors: pathological diagnosis and patient management
I Zemmoura, A Wierinckx, A Vasiljevic, M Jan… - Pituitary, 2013 - Springer
Abstract According to the World Health Organization classification of pituitary tumors, only
tumors with systemic metastasis must be considered as carcinomas. Invasive tumors with …
tumors with systemic metastasis must be considered as carcinomas. Invasive tumors with …
Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses
The molecular pathogenesis of prolactinomas has resisted elucidation; with the exception of
a RAS mutation in a single aggressive prolactinoma, no mutational changes have been …
a RAS mutation in a single aggressive prolactinoma, no mutational changes have been …
Current management of prolactinomas
P Nomikos, M Buchfelder, R Fahlbusch - Journal of neuro-oncology, 2001 - Springer
Prolactinomas constitute the largest group of pituitary adenomas in autopsy series.
However, their relative incidence in recent surgical series is much less impressive since …
However, their relative incidence in recent surgical series is much less impressive since …
Update on prolactinomas. Part 2: treatment and management strategies
The authors present an update on the various treatment modalities and discuss
management strategies for prolactinomas. Prolactinomas are the most common type of …
management strategies for prolactinomas. Prolactinomas are the most common type of …