Prolactin-secreting tumors (prolactinomas) represent the most common pituitary tumor type,
accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and …

Clinically relevant pituitary adenomas are present in about 1 per 1,000 of the general
population and prolactinomas are by far the most common clinical subtype of pituitary …

In recent years the demonstration that human pituitary adenomas are monoclonal in origin
provides further evidence that pituitary neoplasia arise from the replication of a single …

Despite most of the prolactinomas can be treated with endocrine therapy and/or surgery, a
significant percentage of these tumors can be resistant to endocrine treatments and/or recur …

Prolactinoma is the most common pituitary tumour in adults. Macroprolactinomas,
particularly in men, may occasionally exhibit a very aggressive clinical course as evidenced …

Purpose Aggressive prolactinomas are defined as radiologically invasive tumors which
cannot be cured by surgery, and that have an unusually rapid rate of tumor growth despite …

Abstract According to the World Health Organization classification of pituitary tumors, only
tumors with systemic metastasis must be considered as carcinomas. Invasive tumors with …

The molecular pathogenesis of prolactinomas has resisted elucidation; with the exception of
a RAS mutation in a single aggressive prolactinoma, no mutational changes have been …

Prolactinomas constitute the largest group of pituitary adenomas in autopsy series.
However, their relative incidence in recent surgical series is much less impressive since …

The authors present an update on the various treatment modalities and discuss
management strategies for prolactinomas. Prolactinomas are the most common type of …