Dose-dependent beneficial effect of ketone supplement-evoked ketosis on anxiety level in female WAG/Rij rats: Sometimes less is more

E Rauch, C Ari, Z Kovács - Nutrients, 2023 - mdpi.com
While one-third of the population can be affected by anxiety disorders during their lifetime,
our knowledge of the pathophysiology of these disorders is far from complete. Previously, it …

Exogenous ketone supplements reduce anxiety-related behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk rats

C Ari, Z Kovács, G Juhasz, C Murdun… - Frontiers in molecular …, 2016 - frontiersin.org
Nutritional ketosis has been proven effective for seizure disorders and other neurological
disorders. The focus of this study was to determine the effects of ketone supplementation on …

Elevated plus maze test combined with video tracking software to investigate the anxiolytic effect of exogenous ketogenic supplements

C Ari, DP D'Agostino, DM Diamond, M Kindy… - JoVE (Journal of …, 2019 - jove.com
The overall goal of this study is to describe the methodology of the elevated plus maze
(EPM) test in combination with a video tracking software. The purpose of the method is to …

Anxiolytic effect of exogenous ketone supplementation is abolished by adenosine A1 receptor inhibition in Wistar Albino Glaxo/Rijswijk rats

Z Kovács, DP D'Agostino, C Ari - Frontiers in Behavioral …, 2018 - frontiersin.org
Anxiety disorders are one of the most common mental health problems worldwide, but the
exact pathophysiology remains largely unknown. It has been demonstrated previously that …

Therapeutic potential of exogenous ketone supplement induced ketosis in the treatment of psychiatric disorders: review of current literature

Z Kovács, DP D'Agostino, D Diamond, MS Kindy… - Frontiers in …, 2019 - frontiersin.org
Globally, psychiatric disorders, such as anxiety disorder, bipolar disorder, schizophrenia,
depression, autism spectrum disorder, and attention-deficit/hyperactivity disorder (ADHD) …

Age-and sex-dependent modulation of exogenous ketone supplement-evoked effects on blood glucose and ketone body levels in Wistar Albino Glaxo Rijswijk Rats

Z Kovács, B Brunner, DP D'Agostino… - Frontiers in Neuroscience, 2021 - frontiersin.org
In certain disease states, such as epilepsy, the elevation of blood ketone levels with
ketogenic diets (KDs) has beneficial effects, while exogenous ketone supplements (EKSs) …

A combination of ketogenic diet and voluntary exercise ameliorates anxiety and depression-like behaviors in Balb/c mice

H Gumus, R Ilgin, B Koc, O Yuksel, S Kizildag… - Neuroscience …, 2022 - Elsevier
The positive effects of both ketogenic diet (KD) and regular voluntary exercise on anxiety
and depression behavior have been recently reported in rodent animals, but the effects of …

Impact of ketosis on appetite regulation—a review

SE Deemer, EP Plaisance, C Martins - Nutrition Research, 2020 - Elsevier
To reduce the health burden of obesity, it is important to identify safe and practical
treatments that are effective for weight loss while concurrently preventing weight regain. Diet …

Exogenous dietary ketone ester decreases body weight and adiposity in mice housed at thermoneutrality

SE Deemer, RAH Davis, BM Roberts, DL Smith Jr… - …, 2020 - Wiley Online Library
Objective The aim of this study was to examine the effects of a ketone ester (KE)
supplemented diet on energy expenditure (EE) and adiposity in mice housed at 23° C …

Nutritional ketosis affects metabolism and behavior in Sprague-Dawley rats in both control and chronic stress environments

ML Brownlow, SH Jung, RJ Moore… - Frontiers in molecular …, 2017 - frontiersin.org
Nutritional ketosis may enhance cerebral energy metabolism and has received increased
interest as a way to improve or preserve performance and resilience. Most studies to date …