Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?

R Bergquist, J Utzinger, J Keiser - Infectious diseases of poverty, 2017 - Springer
The current approach of morbidity control of schistosomiasis, a helminth disease of poverty
with considerable public health and socioeconomic impact, is based on preventive …

Alternatives to praziquantel for the prevention and control of schistosomiasis

T Spangenberg - ACS Infectious Diseases, 2020 - ACS Publications
Schistosomiasis, a neglected tropical disease provoked by infection with parasitic blood
flukes of the genus Schistosoma, affects almost 240 million people worldwide, and more …

Chemotherapy of schistosomiasis: an update

D Cioli - Parasitology Today, 1998 - cell.com
No major changes have occurred during the past 20 years regarding the therapeutic tools
available to the clinician for the treatment of schistosomiasis. If anything, the two drugs …

Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance

MJ Doenhoff, L Pica-Mattoccia - Expert review of anti-infective …, 2006 - Taylor & Francis
Praziquantel became available for the treatment of schistosomiasis and other trematode-
inflicted diseases in the 1970s. It was revolutionary because it could be administered orally …

Schistosomiasis control: keep taking the tablets

P Hagan, CC Appleton, GC Coles, JR Kusel… - Trends in …, 2004 - cell.com
Despite the limited reports of praziquantel resistance, the relative success of chemotherapy-
based control programmes for schistosomiasis has prompted overdue efforts to expand the …

Antimalarials in the treatment of schistosomiasis

J Keiser, J Utzinger - Current pharmaceutical design, 2012 - ingentaconnect.com
With just one drug used for individual patient management and community-based morbidity
control, the treatment, control, and eventual elimination of schistosomiasis is vulnerable …

Chemotherapy of schistosomiasis: present and future

CR Caffrey - Current opinion in chemical biology, 2007 - Elsevier
Schistosomiasis is a chronic parasitic disease in tropical and subtropical regions and is
associated with a variety of clinical syndromes that may lead to severe morbidity. Over the …

Implementation of human schistosomiasis control: challenges and prospects

A Fenwick, D Rollinson, V Southgate - Advances in parasitology, 2006 - Elsevier
Schistosomiasis is a major disease of public health importance in humans occurring in over
70 countries of the tropics and sub-tropics. In this chapter, the history of the control of …

[PDF][PDF] Antischistosomal natural compounds: present challenges for new drug screens

J de Moraes - Current topics in tropical medicine, 2012 - repositorio.utp.edu.co
Schistosomiasis, or bilharzias, is a neglected disease that remains a considerable public
health problem in tropical and subtropical regions. This parasitic disease is the most …

Use of praziquantel for clinical treatment and morbidity control of schistosomiasis japonica in China: a review of 30 years' experience

C Ming-Gang - Acta tropica, 2005 - Elsevier
Chemotherapy is widely acknowledged as the most important, rapid and cost-effective
method of reducing morbidity due to schistosome infections. The discovery of praziquantel in …