[HTML][HTML] Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1

MR Billman, D Rueda, CRM Bangham - Wellcome open research, 2017 - ncbi.nlm.nih.gov
Background: The human leukaemia virus HTLV-1 expresses essential accessory genes that
manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, tax …

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs

F Rende, I Cavallari, A Corradin… - Blood, The Journal …, 2011 - ashpublications.org
Human T-cell leukemia virus type 1 (HTLV-1) codes for 9 alternatively spliced transcripts
and 2 major regulatory proteins named Tax and Rex that function at the transcriptional and …

Kinetic analysis of human T-cell leukemia virus type 1 gene expression in cell culture and infected animals

M Li, M Kesic, H Yin, L Yu, PL Green - Journal of virology, 2009 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is
associated with a variety of lymphocyte-mediated disorders. It has been hypothesized that a …

[HTML][HTML] Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis

N Rosewick, K Durkin, M Artesi, A Marcais… - Nature …, 2017 - nature.com
Human T-cell leukaemia virus type-1 (HTLV-1) and bovine leukaemia virus (BLV) infect T-
and B-lymphocytes, respectively, provoking a polyclonal expansion that will evolve into an …

Human T-Cell Leukemia Virus Type 2 Antisense Viral Protein 2 Is Dispensable for In Vitro Immortalization but Functions To Repress Early Virus Replication In Vivo

H Yin, P Kannian, N Dissinger, R Haines… - Journal of …, 2012 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 are closely related but
pathogenically distinct human retroviruses. The antisense strand of the HTLV-1 genome …

Regulation of latency in the human T cell leukemia virus, HTLV-1

CRM Bangham, M Miura, A Kulkarni… - Annual Review of …, 2019 - annualreviews.org
The human T cell leukemia virus persists in vivo in 103 to 106 clones of T lymphocytes that
appear to survive for the lifetime of the host. The plus strand of the provirus is typically …

HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication

C Nicot, M Dundr, JM Johnson, JR Fullen, N Alonzo… - Nature medicine, 2004 - nature.com
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) persists despite a vigorous virus-
specific host immune response, and causes adult T-cell leukemia and lymphoma in …

[HTML][HTML] Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling

M Miura, S Dey, S Ramanayake, A Singh… - PLoS …, 2019 - journals.plos.org
The human T cell leukemia virus HTLV-1 establishes a persistent infection in vivo in which
the viral sense-strand transcription is usually silent at a given time in each cell. However …

Permissive sense and antisense transcription from the 5′ and 3′ long terminal repeats of human T-cell leukemia virus type 1

S Laverdure, N Polakowski, K Hoang… - Journal of …, 2016 - Am Soc Microbiol
IMPORTANCE The chromosomally integrated form of the retrovirus human T-cell leukemia
virus type 1 (HTLV-1) contains identical DNA sequences, known as long terminal repeats …

Human T-cell leukemia virus type 2 produces a spliced antisense transcript encoding a protein that lacks a classic bZIP domain but still inhibits Tax2-mediated …

M Halin, E Douceron, I Clerc, C Journo… - Blood, The Journal …, 2009 - ashpublications.org
Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) retroviruses infect T
lymphocytes. The minus strand of the HTLV-1 genome encodes HBZ, a protein that could …