Objective Most pituitary tumours occur sporadically without a genetically identifiable
germline abnormality, a small but increasing proportion present with a genetic defect that …

Background Pituitary tumours are usually benign and relatively common intracranial
tumours, with under-and overexpression of pituitary hormones and local mass effects …

Pituitary tumors are often viewed as benign entities that are rarely associated with significant
rates of mortality or morbidity. These tumors can still be extremely difficult to manage …

The genetic landscape of pituitary adenomas (PAs) is diverse and many of the identified
cases remain of unclear pathogenetic mechanism. Germline genetic defects account for a …

Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

The prevalence of symptomatic pituitary neuroendocrine tumors (PitNETs) is approximately
1 in 1000 in the general population. Most of these tumors occur sporadically and are not part …

Pituitary adenomas represent a group of functionally diverse neoplasms with relatively high
prevalence in the general population. Most occur sporadically, but inherited genetic …

Pituitary adenomas are common tumors of the adenohypophysis which can cause
considerable morbidity, due to excessive hormonal secretion or compression and local …

Pituitary adenomas are benign intracranial neoplasms that can result in morbidity owing to
local invasion and/or excessive or deficient hormone production. The prevalence of …

Background: Pituitary adenomas occur in a familial setting in about 5% of all cases and over
half of these are due to multiple endocrine neoplasia type 1 (MEN1) and Carney complex …