Pituitary adenomas are currently classified by histological, immunocytochemical and
numerous ultrastructural characteristics lacking unequivocal prognostic correlations. We …

Abstract Background and Objective: In 2004, the World Health Organization defined atypical
pituitary adenomas as those with a Ki-67 expression> 3%, an excessive p53 expression and …

Objective and design A clinicopathological score has been proposed by Trouillas et al. to
predict the evolution of pituitary adenomas. Aim of our study was to perform an independent …

Pituitary adenomas are common intracranial tumors that are mainly considered as benign.
Rarely, these tumors can exhibit an aggressive behavior, characterized by gross invasion of …

Pituitary adenomas originating in adenohypophysial cells represent the most common
neoplasms of the sella turcica. The pathologist's goal is the optimal diagnosis and …

Pituitary adenomas are considered benign tumors, but approximately 10% of them can have
an aggressive behavior and more rarely (0.2%) can present metastasis, being classified as …

The WHO categorizes pituitary tumours as typical adenomas, atypical adenomas and
pituitary carcinomas, with typical adenomas constituting the major class. However, the WHO …

Pituitary adenomas (PAs) are benign lesions; nonetheless, some PAs exhibit aggressive
behaviors, which lead to recurrence. The impact of pituitary dysfunction, invasion-related …

Background Most pituitary neuroendocrine tumors (PitNETs) show benign behavior, but a
substantial number are invasive, recur, or resist medical treatment. Based on a retrospective …

Pituitary adenohypophyseal tumors are considered as benign and termed “adenomas”.
However, many tumors are invasive and a proportion of these exhibit an “aggressive …