Real-life clinical impact of a five-tiered classification of pituitary tumors

N Sahakian, R Appay, N Resseguier… - European journal of …, 2022 - academic.oup.com
Introduction Usually benign, pituitary tumors (PT) can be invasive and aggressive with a
propensity to progress and/or recur. Trouillas's clinicopathological classification attempts to …

Are aggressive pituitary tumors and carcinomas two sides of the same coin? Pathologists reply to clinician's questions

J Trouillas, ML Jaffrain-Rea, A Vasiljevic… - Reviews in Endocrine …, 2020 - Springer
Pituitary adenohypophyseal tumors are considered as benign and termed “adenomas”.
However, many tumors are invasive and a proportion of these exhibit an “aggressive …

Risk of recurrence in pituitary neuroendocrine tumors: a prospective study using a five-tiered classification

G Raverot, E Dantony, J Beauvy… - The Journal of …, 2017 - academic.oup.com
Background Most pituitary neuroendocrine tumors (PitNETs) show benign behavior, but a
substantial number are invasive, recur, or resist medical treatment. Based on a retrospective …

A practical algorithm to predict postsurgical recurrence and progression of pituitary neuroendocrine tumours (PitNET)s

F Guaraldi, M Zoli, A Righi, D Gibertoni… - Clinical …, 2020 - Wiley Online Library
Abstract Objective Pituitary neuroendocrine tumours (PitNET) s can be aggressive, thus
presenting local invasion, postsurgical recurrence and/or resistance to treatment …

Advances and controversies in the classification and grading of pituitary tumors

ER Laws, DL Penn, CS Repetti - Journal of Endocrinological Investigation, 2019 - Springer
Background Pituitary tumors are common lesions, and they represent the second most
frequent primary brain tumor. Their classification has undergone several changes over time …

How to classify and define pituitary tumors: recent advances and current controversies

C Dai, J Kang, X Liu, Y Yao, H Wang… - Frontiers in …, 2021 - frontiersin.org
Pituitary tumors are very complex and heterogeneous and have a very wide range of
proliferative and aggressive behaviors, and how to define and classify these tumors remains …

Aggressive and malignant pituitary tumours: state-of-the-art

D Dworakowska, AB Grossman - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Pituitary adenomas are unique in multiple ways. They are rarely malignant in terms of
metastases; yet, they may be aggressive. Their cancerous potential is defined in a classic …

Initial pathology in aggressive pituitary tumours and carcinomas: 2b or not 2b?—that is the question

J Trouillas, P Burman, M Losa… - European journal of …, 2023 - academic.oup.com
From a cohort of 171 patients comprising 121 aggressive pituitary tumours (APT) and 50
pituitary carcinomas (PC), the clinicopathological or five-tiered classification based on …

Aggressive pituitary adenomas—diagnosis and emerging treatments

A Di Ieva, F Rotondo, LV Syro, MD Cusimano… - Nature Reviews …, 2014 - nature.com
The WHO categorizes pituitary tumours as typical adenomas, atypical adenomas and
pituitary carcinomas, with typical adenomas constituting the major class. However, the WHO …

[PDF][PDF] Clinicopathological classification and molecular markers of pituitary tumours for personalized therapeutic strategies

G Raverot, E Jouanneau, J Trouillas - Eur J Endocrinol, 2014 - Citeseer
Pituitary tumours, the most frequent intracranial tumour, are historically considered benign.
However, various pieces of clinical evidence and recent advances in pathological and …