The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits

W Bönigk, J Bradley, F Müller, F Sesti… - Journal of …, 1999 - Soc Neuroscience
Cyclic nucleotide-gated (CNG) channels play central roles in visual and olfactory signal
transduction. In the retina, rod photoreceptors express the subunits CNCα1 and CNCβ1a. In …

Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina

A Gerstner, X Zong, F Hofmann, M Biel - Journal of Neuroscience, 2000 - Soc Neuroscience
Cyclic nucleotide-gated (CNG) channels play a key role in olfactory and visual transduction.
Native CNG channels are heteromeric complexes consisting of the principal α subunits …

An isoform of the rod photoreceptor cyclic nucleotide-gated channel β subunit expressed in olfactory neurons

A Sautter, X Zong, F Hofmann… - Proceedings of the …, 1998 - National Acad Sciences
Sensory transduction in olfactory neurons involves the activation of a cyclic nucleotide-gated
(CNG) channel by cAMP. Previous studies identified a CNG channel α subunit (CNG2) and …

Structure and function of cyclic nucleotide-gated channels.

WN Zagotta, SA Siegelbaum - Annual review of neuroscience, 1996 - europepmc.org
Cyclic nucleotide-gated (CNG) channels play important roles in both visual (Yau & Baylor
1989) and olfactory (Zufall et al 1994) signal transduction. The cloning of the gene coding for …

Widespread expression of olfactory cyclic nucleotidegated channel genes in rat brain: implications for neuronal signalling

PA Kingston, F Zufall, CJ Barnstable - Synapse, 1999 - Wiley Online Library
The cyclic nucleotides cAMP and cGMP are important intracellular messengers involved in a
wide variety of signal transduction events in the nervous system. It has been proposed that …

Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP.

J Bradley, JUN Li, N Davidson… - Proceedings of the …, 1994 - National Acad Sciences
Olfactory receptor neurons respond to odorant stimulation with a rapid increase in
intracellular cAMP that opens cyclic nucleotide-gated (cng) cation channels. cng channels in …

Cyclic NucleotideGated Channels: Molecular Mechanisms of Activation

MC BROILLET, S Firestein - Annals of the New York Academy …, 1999 - Wiley Online Library
Activation of cyclic nucleotidegated (CNG) channels represents the final step in the
transduction pathways in both vision and olfaction. Over the past several years, CNG …

[HTML][HTML] Cyclic nucleotide-gated ion channels in sensory transduction

S Pifferi, A Boccaccio, A Menini - FEBS letters, 2006 - Elsevier
Cyclic nucleotide-gated (CNG) channels, directly activated by the binding of cyclic
nucleotides, were first discovered in retinal rods, cones and olfactory sensory neurons. In the …

Calcium/calmodulin modulation of olfactory and rod cyclic nucleotide-gated ion channels

MC Trudeau, WN Zagotta - Journal of Biological Chemistry, 2003 - ASBMB
Cyclic nucleotide-gated (CNG) ion channels mediate sensory transduction in olfactory
sensory neurons and retinal photoreceptor cells. In these systems, internal …

[HTML][HTML] Cyclic nucleotide-gated ion channels

UB Kaupp, R Seifert - Physiological reviews, 2002 - journals.physiology.org
Cyclic nucleotide-gated (CNG) channels are nonselective cation channels first identified in
retinal photoreceptors and olfactory sensory neurons (OSNs). They are opened by the direct …