Accurate protocols and methods to robustly detect the mosaic loss of chromosome Y (mLOY)
are needed given its reported role in cancer, several age-related disorders and overall male …

Background Accurate protocols and methods to robustly detect the mosaic loss of
chromosome Y (mLOY) are needed given its reported role in cancer, several age-related …

Background Mosaic loss of chromosome Y (LOY) is the most common somatic mutation and
is associated with all-cause mortality, non-haematological cancers and Alzheimer's disease …

Mosaic loss of Y (mLOY) is the most common somatic chromosomal alteration detected in
human blood. The presence of mLOY is associated with altered blood cell counts and …

Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is a somatic event in
which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY …

Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural
somatic event. Previous studies have indicated age and cigarette smoking increase the risk …

Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number
alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential …

Zhou et al. reply—A revised Correspondence by Forsberg et al. 1 (whose authors include
the founders of CRAY Innovation, LA Forsberg and JP Dumanski) posits that the …

As human life expectancy increases substantially and aging is the primary risk factor for
most chronic diseases, there is an urgent need for advancing the development of post …

Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …