Osteoarthritis (OA) is a joint disorder that is highly extended in the global population. Several
researches and therapeutic strategies have been probed on OA but without satisfactory long …

Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …

Osteoarthritis (OA) is a complex disease of the joint for which current treatments are
unsatisfactory, thus motivating development of tissue engineering (TE)-based therapies. To …

Articular cartilage injuries and degenerative joint diseases are responsible for progressive
pain and disability in millions of people worldwide, yet there is currently no treatment …

It is well known that the biomechanical and tribological performance of articular cartilage is
inextricably linked to its extracellular matrix (ECM) structure and zonal heterogeneity …

Articular cartilage defects often progress to osteoarthritis, which negatively impacts quality of
life for millions of people worldwide and leads to high healthcare expenditures. Tissue …

Mechanical stimuli have fundamental roles in articular cartilage during health and disease.
Chondrocytes respond to the physical properties of the cartilage extracellular matrix (ECM) …

There is an urgent demand for long term solutions to improve osteoarthritis treatments in the
ageing population. There are drugs that control the pain but none that stop the progression …

I t has been well-established that mechanical stimuli are crucial to the healthy development
and maintenance of native articular cartilage. Consequently, physical factors have become …

Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …