This chapter examines neurobiological development in normal and illustrative highrisk
conditions and mental disorders. It reviews relevant findings on neural plasticity and their …

Resilience and adaptation in the face of early genetic or environmental risk has become a
major interest in child psychiatry over recent years. However, we still remain far from an …

While research on focal perinatal lesions has provided evidence for recovery of function,
much less is known about processes of brain adaptation resulting from mild but widespread …

Advances in the fields of cognitive and affective developmental neuroscience,
developmental psychopathology, neurobiology, genetics, and applied behavior analysis …

A pivotal period in human brain and behavioral development occurs in the first years of life.
These years are normally characterized by a degree and variety of neuroanatomical change …

Objective: To review general principles of brain development, identify basic principles of
brain plasticity, and discuss factors that influence brain development and plasticity. Method …

Autistic symptoms begin in the first years of life, and recent magnetic resonance imaging
studies have discovered brain growth abnormalities that precede and overlap with the onset …

Autism is a behaviorally defined disorder characterized by a broad constellation of
symptoms. Numerous studies directed to the biological substrate demonstrate clear effects …

Dramatic gains in knowledge have been made in the fields of neuroscience, human
development, and developmental psychopathology during the past quarter of a century …

Studies of infant siblings of older autistic probands, who are at elevated risk for autism, have
demonstrated that the defining features of autism are not present in the first year of life but …