Isolation methods influence the protein corona composition on gold-coated iron oxide nanoparticles

KNL Hoang, KE Wheeler, CJ Murphy - Analytical Chemistry, 2022 - ACS Publications
Upon exposure to a biological environment, nanoparticles (NPs) acquire biomolecular
coatings, the most studied of which is the protein corona. This protein corona gives NPs a …

Concentration and composition of the protein corona as a function of incubation time and serum concentration: an automated approach to the protein corona

KM Poulsen, CK Payne - Analytical and Bioanalytical Chemistry, 2022 - Springer
Nanoparticles in contact with proteins form a “corona” of proteins adsorbed on the
nanoparticle surface. Subsequent biological responses are then mediated by the adsorbed …

Complementary mass spectrometric techniques for the quantification of the protein corona: a case study on gold nanoparticles and human serum proteins

N Fernández-Iglesias, J Bettmer - Nanoscale, 2015 - pubs.rsc.org
Once nanoparticles enter a biological system, it is known that their surface is instantly
covered by the biomolecules present with preference to proteins. This protein corona has …

[HTML][HTML] Silver nanoparticle protein corona composition in cell culture media

JH Shannahan, X Lai, PC Ke, R Podila, JM Brown… - PloS one, 2013 - journals.plos.org
The potential applications of nanomaterials as drug delivery systems and in other products
continue to expand. Upon introduction into physiological environments and driven by …

Protein corona analysis of silver nanoparticles links to their cellular effects

S Juling, A Niedzwiecka, L Böhmert… - Journal of proteome …, 2017 - ACS Publications
The breadth of applications of nanoparticles and the access to food-associated consumer
products containing nanosized materials lead to oral human exposure to such particles. In …

Nanoparticle size matters in the formation of plasma protein coronas on Fe3O4 nanoparticles

Z Hu, H Zhang, Y Zhang, R Wu, H Zou - Colloids and surfaces b …, 2014 - Elsevier
When nanoparticles (NPs) enter into biological systems, proteins would interact with NPs to
form the protein corona that can critically impact the biological identity of the nanomaterial …

Mass spectrometric approach for the analysis of the hard protein corona of nanoparticles in living cells

GP Szekeres, N Fernández-Iglesias, J Kneipp… - Journal of …, 2020 - Elsevier
The diagnostic and therapeutic application of nanoparticles requires comprehensive
knowledge of their interaction with the biomolecular surroundings. The formation of the …

Development of a fast and simple method for the isolation of superparamagnetic iron oxide nanoparticles protein corona from protein-rich matrices

MG Soliman, DN Trinh, C Ravagli, P Meleady… - Journal of Colloid and …, 2024 - Elsevier
The adsorption of proteins onto the surface of nanoparticle (NP) leads to the formation of the
so-called “protein corona” as consisting both loosely and tightly bound proteins. It is well …

Interaction of gold and silver nanoparticles with human plasma: Analysis of protein corona reveals specific binding patterns

W Lai, Q Wang, L Li, Z Hu, J Chen, Q Fang - Colloids and Surfaces B …, 2017 - Elsevier
Determining how nanomaterials interact with plasma will assist in understanding their effects
on the biological system. This work presents a systematic study of the protein corona formed …

[HTML][HTML] Quantification of the PEGylated gold nanoparticles protein corona. Influence on nanoparticle size and surface chemistry

R Nicoară, M Ilieș, A Uifălean, CA Iuga, F Loghin - Applied Sciences, 2019 - mdpi.com
The interactions of nanoparticles with living organisms are driven by an interface called the
protein corona. This interface is formed when nanoparticles are introduced in biological …