Several lines of evidence suggest a link between the α7 neuronal nicotinic acetylcholine
receptor (nAChR) and brain disorders including schizophrenia, Alzheimer's disease, and …

The α7 nicotinic acetylcholine receptor (nAChR) is a potential therapeutic target for the
treatment of cognitive deficits associated with schizophrenia, Alzheimer's disease …

Augmentation of nicotinic α7 receptor function is considered to be a potential therapeutic
strategy aimed at ameliorating cognitive and mnemonic dysfunction in relation to debilitating …

Accumulating data suggest that α7 nicotinic acetylcholine receptors (α7nAChRs) are an
important therapeutic target for the treatment of Alzheimer's disease (AD) and schizophrenia …

The α7 nicotinic acetylcholine receptor (nAChR) is a promising target for treatment of
cognitive dysfunction associated with Alzheimer's disease and schizophrenia. Here, we …

Nicotinic acetylcholine receptors (nAChRs) are pentameric ligandgated ion channels
involved in many physiological and pathological processes. In vertebrates, there are …

Positive allosteric modulators of α7 nicotinic acetylcholine receptors (nAChRs) have
attracted considerable interest as potential tools for the treatment of neurological and …

Progress in the fields of neuroscience and molecular biology has identified the forebrain
cholinergic system as being important in many higher order brain functions. Further analysis …

The α7 nicotinic acetylcholine receptor (nAChR), a homopentameric, rapidly activating and
desensitizing ligand-gated ion channel with relatively high degree of calcium permeability, is …

Schizophrenic patients are thought to have an impaired ability to process sensory
information. This deficit leads to disrupted auditory gating measured electrophysiologically …