• Introduction• ECM: composition and structureCollagenLamininFibronectinElastin
NidogenGlycosaminoglycansPerlecanSyndecansReceptors for ECM molecules• …

The vascular network is a series of linked conduits of blood vessels composed of the
endothelium, a monolayer of cells that adorn the vessel lumen and surrounding layer (s) of …

The vascular network is an integral component of most organs. Beyond assuring an
adequate supply of oxygen and nutrients for normal tissue function, vascular structures …

Blood vessels are highly organized and complex structure, which are far more than simple
tubes conducting the blood to almost any tissue of the body. They are able to autonomously …

Extracellular matrix proteins form the basic structure of blood vessels. Along with providing
basic structural support to blood vessels, matrix proteins interact with different sets of …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …

During angiogenesis, endothelial cell growth, migration, and tube formation are regulated by
pro-and anti-angiogenic factors, matrix-degrading proteases, and cell–extracellular matrix …

The extracellular matrix (ECM) of blood vessels, which is composed of both the vascular
basement membrane (BM) and the interstitial ECM is identified as a crucial component of …

Extracellular matrix (ECM) within the vascular network provides both a structural and
regulatory role. The ECM is a dynamic composite of multiple proteins that form structures …

The extracellular matrix (ECM) is a complex network of proteins, glycoproteins,
proteoglycans, and polysaccharides. Through multiple interactions with each other and the …