Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics

F Gong, N Yang, X Wang, Q Zhao, Q Chen, Z Liu… - Nano Today, 2020 - Elsevier
The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …

Tumor microenvironment sensitive nanocarriers for bioimaging and therapeutics

H Park, G Saravanakumar, J Kim… - Advanced Healthcare …, 2021 - Wiley Online Library
The tumor microenvironment (TME), which is composed of cancer cells, stromal cells,
immune cells, and extracellular matrices, plays an important role in tumor growth and …

Tumor microenvironment‐enabled nanotherapy

L Wang, M Huo, Y Chen, J Shi - Advanced healthcare materials, 2018 - Wiley Online Library
Cancer is now one of the world's leading threats to human health. With the development of
oncology in both biology and biomedicine, it has been demonstrated that abnormal …

Engineered drug delivery nanosystems for tumor microenvironment normalization therapy

B Yang, F Meng, J Zhang, K Chen, S Meng, K Cai… - Nano Today, 2023 - Elsevier
As a complex" soil" ecosystem, the tumor microenvironment (TME) plays a crucial role in the
occurrence, development and metastasis of tumors. Reprogramming TME can block the …

Tumor microenvironment-responsive nanoparticles for cancer theragnostic applications

S Uthaman, KM Huh, IK Park - Biomaterials research, 2018 - spj.science.org
Background Cancer is one of the deadliest threats to human health. Abnormal
physiochemical conditions and dysregulated biosynthetic intermediates in the tumor …

Precise subcellular organelle targeting for boosting endogenous‐stimuli‐mediated tumor therapy

W Zhen, S An, S Wang, W Hu, Y Li, X Jiang… - Advanced …, 2021 - Wiley Online Library
Though numerous external‐stimuli‐triggered tumor therapies, including phototherapy,
radiotherapy, and sonodynamic therapy have made great progress in cancer therapy, the …

Tumor Therapy Strategies Based on Microenvironment‐Specific Responsive Nanomaterials

Z Zhang, C Ding, T Sun, L Wang… - Advanced Healthcare …, 2023 - Wiley Online Library
The tumor microenvironment (TME) is a complex and variable region characterized by
hypoxia, low pH, high redox status, overexpression of enzymes, and high‐adenosine …

Tumour microenvironment responsive nanoconstructs for cancer theranostic

A Gulzar, J Xu, C Wang, F He, D Yang, S Gai, P Yang… - Nano today, 2019 - Elsevier
The tumour mass is made up of not only of a heterogeneous population of cancer cells
nonetheless also a mixture of resident as well as the infiltrating host cells, secreted factors …

Emerging nanomedicines strategies focused on tumor microenvironment against cancer recurrence and metastasis

Y Feng, Z Liao, H Zhang, X Xie, F You, X Liao… - Chemical Engineering …, 2023 - Elsevier
Every stage of cancer metastasis, immune surveillance evasion, and therapeutic resistance
is influenced by tumor microenvironment (TME). In light of this, nanomedicines design based …

The recent progress of inorganic‐based intelligent responsive nanoplatform for tumor theranostics

Z Yang, H Chen - View, 2022 - Wiley Online Library
Inorganic nanoplatform exhibits great potentials in drug delivery and responsive release
attributed to its inherent physicochemical properties, good biocompatibility, surface …