[HTML][HTML] Adverse outcomes of polypharmacy in older people: systematic review of reviews

LE Davies, G Spiers, A Kingston, A Todd… - Journal of the American …, 2020 - Elsevier
Objective Polypharmacy is widespread among older people, but the adverse outcomes
associated with it are unclear. We aim to synthesize current evidence on the adverse health …

Clinical consequences of polypharmacy in elderly

RL Maher, J Hanlon, ER Hajjar - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

Health outcomes associated with polypharmacy in communitydwelling older adults: a systematic review

TR Fried, J O'Leary, V Towle… - Journal of the …, 2014 - Wiley Online Library
Objectives To summarize evidence regarding the health outcomes associated with
polypharmacy, defined as number of prescribed medications, in older communitydwelling …

Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

Polypharmacy in elderly patients

ER Hajjar, AC Cafiero, JT Hanlon - The American journal of geriatric …, 2007 - Elsevier
Background: Polypharmacy (ie, the use of multiple medications and/or the administration of
more medications than are clinically indicated, representing unnecessary drug use) is …

How chronic is polypharmacy in old age? A longitudinal nationwide cohort study

JW Wastesson, L Morin, ML Laroche… - Journal of the …, 2019 - Wiley Online Library
OBJECTIVE To evaluate the chronicity of polypharmacy among older adults and to identify
factors associated with chronic polypharmacy. DESIGN Longitudinal cohort study using …

Association between polypharmacy and mortality in the older adults: A systematic review and meta-analysis

Y Li, X Zhang, L Yang, Y Yang, G Qiao, C Lu… - Archives of Gerontology …, 2022 - Elsevier
Background: Polypharmacy and related adverse consequences are common in the older
adults, especially mortality, but the causality of this relationship remains unclear. This meta …

Prevalence and factors associated with polypharmacy: a systematic review and meta-analysis

M Delara, L Murray, B Jafari, A Bahji, Z Goodarzi… - BMC geriatrics, 2022 - Springer
Introduction Polypharmacy is commonly associated with adverse health outcomes. There
are currently no meta-analyses of the prevalence of polypharmacy or factors associated with …

An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …