Increased resistance to portal blood flow is the primary factor in the pathophysiology of
portal hypertension, and is mainly determined by the morphological changes occurring in …

In cirrhotic patients under pharmacologic treatment for portal hypertension, a reduction in
hepatic venous pressure gradient (HVPG) of≥ 20% of baseline or to≤ 12 mm Hg markedly …

We report the results of adapting medical therapy to the monitoring of hemodynamic
response in the prevention of a first variceal bleeding or rebleeding in patients with cirrhosis …

In addition to complications relating to the liver, patients with cirrhosis and portal
hypertension develop extrahepatic functional disturbances of multiple organ systems. This …

THERE is much to be learned regarding the natural history of portal hypertension in
cirrhosis. This is a natural consequence of the lack of a technic for direct measurement of …

BACKGROUND/AIMS: Following treatment with beta blockers in patients with cirrhosis and
portal hypertension, reduction of hepatic venous pressure gradient (HVPG) to< 12 mmHg or …

The management of portal hypertension should be based on an updated knowledge of its
natural history. Portal hypertension is an almost unavoidable complication of cirrhosis, and it …

In the prevention of variceal rebleeding, it is already established that hemodynamic
response to drug treatment (decrease in hepatic venous pressure gradient [HVPG] to 12 mm …

Noninvasive measurements of variceal pressure adequately reflect the hemodynamic effects
of propranolol on portal hypertension. However, the prognostic value of variceal pressure …

Many of the complications of cirrhosis reflect the presence of portal hypertension, which is
commonly expressed as the hepatic venous pressure gradient (HVPG). Baseline and repeat …