Enzyme-responsive liposomes for the delivery of anticancer drugs

F Fouladi, KJ Steffen, S Mallik - Bioconjugate Chemistry, 2017 - ACS Publications
Liposomes are nanocarriers that deliver the payloads at the target site, leading to
therapeutic drug concentrations at the diseased site and reduced toxic effects in healthy …

[HTML][HTML] Updates on responsive drug delivery based on liposome vehicles for cancer treatment

MP Nikolova, EM Kumar, MS Chavali - Pharmaceutics, 2022 - mdpi.com
Liposomes are well-known nanoparticles with a non-toxic nature and the ability to
incorporate both hydrophilic and hydrophobic drugs simultaneously. As modern drug …

[HTML][HTML] Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review

MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

A General Approach to EnzymeResponsive Liposomes

J Lou, MD Best - Chemistry–A European Journal, 2020 - Wiley Online Library
Liposomes are effective nanocarriers due to their ability to deliver encapsulated drugs to
diseased cells. Nevertheless, liposome delivery would be improved by enhancing the ability …

Surface-active liposomes for targeted cancer therapy

S Sofou - Nanomedicine, 2007 - Taylor & Francis
An overview of liposome-based drug-delivery carriers to cancer cells is presented.
Properties related to interfacial interactions between liposomes and the biological milieu that …

Dual-targeting and stimuli-triggered liposomal drug delivery in cancer treatment

N AlSawaftah, WG Pitt, GA Husseini - ACS pharmacology & …, 2021 - ACS Publications
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …

Liposomal drug delivery systems for targeted cancer therapy: is active targeting the best choice?

S Fathi, AK Oyelere - Future medicinal chemistry, 2016 - Taylor & Francis
Liposomes are biodegradable and biocompatible self-forming spherical lipid bilayer
vesicles. They can encapsulate and deliver one or more hydrophobic and hydrophilic …

[HTML][HTML] Liposomes for tumor targeted therapy: a review

S Wang, Y Chen, J Guo, Q Huang - International journal of molecular …, 2023 - mdpi.com
Liposomes, the most widely studied nano-drug carriers in drug delivery, are sphere-shaped
vesicles consisting of one or more phospholipid bilayers. Compared with traditional drug …

Updates on the use of liposomes for active tumor targeting in cancer therapy

W Yan, SSY Leung, KKW To - Nanomedicine, 2020 - Taylor & Francis
In the development of cancer chemotherapy, besides the discovery of new anticancer drugs,
a variety of nanocarrier systems for the delivery of previously developed and new …

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities

L Belfiore, DN Saunders, M Ranson… - Journal of controlled …, 2018 - Elsevier
The development of therapeutic resistance to targeted anticancer therapies remains a
significant clinical problem, with intratumoral heterogeneity playing a key role. In this context …