Salamanders have been hailed as champions of regeneration, exhibiting a remarkable
ability to regrow tissues, organs and even whole body parts, eg their limbs. As such …

The most extensive regenerative ability in adult vertebrates is found in the salamanders.
Although it is often suggested that regeneration is an ancestral property for vertebrates, our …

Although regeneration of tissues occurs in all adult tetrapods, the ability to regenerate
complex structures such as limbs is limited to urodeles (newts and salamanders). Given that …

Salamander limb regeneration is a classical model of tissue morphogenesis and patterning.
Through recent advances in cell labeling and molecular analysis, a more precise …

Urodele amphibians such as the axolotl are the champions of tissue regeneration amongst
vertebrates. These animals have mastered the ability to repair and replace most of their …

The failure to replace damaged body parts in adult mammals results from a muted growth
response and fibrotic scarring. Although infiltrating immune cells play a major role in …

Understanding how to promote organ and appendage regeneration is a key goal of
regenerative medicine. The frog, Xenopus, can achieve both scar-free healing and tissue …

Salamanders have the remarkable ability to regenerate lost body parts and injured organs.
This regenerative ability requires fully-differentiated cells in the vicinity of the injury to …

Humans and other mammals are limited in their natural abilities to regenerate lost body
parts. By contrast, many salamanders are highly regenerative and can spontaneously …

Salamanders regenerate appendages via a progenitor pool called the blastema. The
cellular mechanisms underlying regeneration of muscle have been much debated but have …