As a regulatory cell death mode defined in recent years, Ferroptosis is mainly characterized
by increased intracellular free iron and the accumulation of lipid peroxides. Ferroptosis is …

Ferroptosis is a type of programmed cell death depending on iron and reactive oxygen
species. This unique cell death process has attracted a great deal of attention in the field of …

The treatment of cancer mainly involves surgical excision supplemented by radiotherapy
and chemotherapy. Chemotherapy drugs act by interfering with tumor growth and inducing …

Ferroptosis, as a newly discovered non-apoptotic cell death mode, is beginning to be
explored in different cancer. The particularity of ferroptosis lies in the accumulation of iron …

Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

Ferroptosis is a newly discovered form of iron-dependent cell death, which is different from
other death forms. The main characteristics of ferroptosis are:(1) Amino acid metabolism.(2) …

At present, more than one cell death pathways have been found, one of which is ferroptosis.
Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid …

Ferroptosis represents a form of programmed cell death that is propelled by iron-dependent
lipid peroxidation, thereby being distinguished by the prominent features of iron …

Ferroptosis is a new type of non-apoptotic regulated cell death (RCD) driven by unrestricted
lethal lipid peroxidation, which is totally distinct from other forms of RCD in genetic and …

Objective This article reviews the specific mechanism of ferroptosis in cancer and introduces
in detail the opportunities and challenges of ferroptosis-based cancer therapy, aiming to …