Celastrol, a quinonemethide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …

Celastrol, a principal bioactive ingredient of Tripterygium wilfordii Hook F, has gained
extensive exploration due to its unique structure features and multiple promising biological …

In the recent years, much attention has been focused on identifying bioactive compounds
from medicinal plants that could be employed in therapeutics, which is attributed to their …

Celastroid natural products, triterpenes, have been and continue to be investigated in
clinical trials. Celastrol, and for that matter any member of the celastroid family, was …

The central nervous system (CNS) is a vital part of the human nervous system, and the
incidence of CNS disease is increasing year by year, which has become a major public …

Celastrol is a highly investigated anticancer moiety. It is a pentacyclic triterpenoid, isolated
several decades ago with promising role in chemoprevention. Celastrol has been found to …

Celastrol (also called tripterine) is a quinone methide triterpene isolated from the root extract
of Tripterygium wilfordii (thunder god vine in traditional Chinese medicine). Over the past …

Celastrol, a natural bioactive ingredient derived from Tripterygium wilfordii Hook F, exhibits
significant broad-spectrum anticancer activities for the treatment of a variety of cancers …

Celastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine
Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular …

Celastrol is one of the most studied natural products. Our studies show for the first time that
celastrol can bind to its target protein via specific noncovalent interactions that position …