Objective To determine whether use of metal-on-metal bearing surfaces is associated with
an increased risk of a diagnosis of cancer in the early years after total hip replacement and …

Background and purpose Over 1 million metal-on-metal hip replacements were implanted.
Even well-functioning implants produce wear debris that can cause tissue damage …

Background There are concerns that metal-on-metal hip implants may cause cancer. The
objective of this study was to evaluate patterns and timing of risk of cancer in patients with …

Objective To assess the risk of cancer associated with modern primary metal-on-metal hip
replacements. Design Population based study. Setting Nationwide retrospective …

Background: Release and dispersion of particles arising from corrosion and wear of total hip
arthroplasty (THA) components has raised concerns about a possible increased risk of …

All patients with total hip arthroplasty (THA) are exposed to soluble or particulate forms of Co
and Cr. Adverse effects of these wear products are not known. Data from Nordic registries is …

Objectives To compare 10 year mortality rates among patients undergoing metal-on-metal
hip resurfacing and total hip replacement in England. Design Retrospective cohort study …

Background and purpose—Metal-on-metal hip implants have been widely used, especially
in the USA, Australia, England and Wales, and Finland. We assessed risk of death and …

Background Total hip replacement (THR) is extremely common. Some prostheses fail,
particularly in younger patients, and need to be revised, most commonly for loosening …

Background and purpose—Despite the increasing number of total hip replacements (THRs),
their systemic influence is still not known. We have studied the influence of specific features …