Pituitary adenomas (PAs) are benign lesions; nonetheless, some PAs exhibit aggressive
behaviors, which lead to recurrence. The impact of pituitary dysfunction, invasion-related …

Background The 2004 World Health Organization classification introduced atypical pituitary
adenoma (aPA), which was equivocally defined as invasion with increased mitotic activity …

The fourth edition of the World Health Organization (WHO) classification of pituitary tumors
recommended evaluation of tumor proliferation and invasion to identify aggressiveness. We …

Pituitary adenomas are currently classified by histological, immunocytochemical and
numerous ultrastructural characteristics lacking unequivocal prognostic correlations. We …

Abstract Background and Objective: In 2004, the World Health Organization defined atypical
pituitary adenomas as those with a Ki-67 expression> 3%, an excessive p53 expression and …

Though pituitary adenomas (PA) are considered benign, some of them exhibit invasive
behaviors such as recurrence and low rate of total surgical resection. Reliable prognostic …

Abstract Ki-67 Labeling Index is an immunocytochemical marker of cell proliferation. The
correlation of Ki-67 expression with pituitary adenomas recurrence has been investigated …

Context: Nonfunctioning pituitary adenomas are commonly diagnosed as large tumors. Most
are detected incidentally during imaging studies or as a result of neurological …

Context: The factors associated with pituitary adenoma (PA) growth rate remain unclear.
Objective: The objective of the study was to establish whether the preoperative growth and …

Pituitary adenomas are classified as typical or atypical, invasive or noninvasive, and
aggressive or nonaggressive based on pathological features, radiological findings, and …