[HTML][HTML] NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues

B Perbal - Molecular Pathology, 2001 - ncbi.nlm.nih.gov
The CCN family of genes presently consists of six distinct members encoding proteins that
participate in fundamental biological processes such as cell proliferation, attachment …

A structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesis

N Planque, B Perbal - Cancer cell international, 2003 - Springer
Abstract The CCN (C YR61 [Cystein-rich61]/C TGF [connective tissue growth factor]/N OV
[Nephroblastoma overexpressed]) proteins constitute a family of regulatory factors involved …

The expression of ccn3 (nov) gene in musculoskeletal tumors

MC Manara, B Perbal, S Benini, R Strammiello… - The American journal of …, 2002 - Elsevier
The CCN3 (NOV) protein belongs to the CCN [cysteine-rich CYR61, connective tissue
growth factor (CTGF), nephroblastoma overexpressed gene (Nov)] family of growth …

[PDF][PDF] The CCN family proteins in carcinogenesis

A Dhar, A Ray - Exp Oncol, 2010 - scholar.archive.org
The CCN (Cyr61 (cysteine-rich protein 61), CTGF (connective tissue growth factor), Nov
(nephroblastoma overexpressed)) fami ly consists of six members that belong to …

The CCN family of genes: a perspective on CCN biology and therapeutic potential

H Yeger, B Perbal - Journal of cell communication and signaling, 2007 - Springer
The CCN family of genes currently comprises six secreted proteins (designated CCN1–6
after Cyr61/CCN1; ctgf/CCN2; Nov/CCN3; WISP1/CCN4; WISP2/CCN5, WISP3/CCN6) with …

[图书][B] CCN proteins: a new family of cell growth and differentiation regulators

BV Perbal, M Takigawa - 2005 - books.google.com
The CCN Proteins are thought to play key roles in the biology ofnormal cell, tissue, organ,
and body, and altered expression of CCNproteins is associated with several pathologies …

CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family

CG Lin, SJ Leu, N Chen, CM Tebeau, SX Lin… - Journal of Biological …, 2003 - ASBMB
CCN3 (NOV) is a matricellular protein of the CCN family, which also includes CCN1
(CYR61), CCN2 (CTGF), CCN4 (WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3). During …

Levels of Expression of CYR61 and CTGF Are Prognostic for Tumor Progression and Survival of Individuals with Gliomas

D Xie, D Yin, HJ Wang, GT Liu, R Elashoff, K Black… - Clinical Cancer …, 2004 - AACR
The biological properties of CCN proteins include stimulation of cell proliferation, migration,
and adhesion, as well as angiogenesis and tumorigenesis. We quantified CYR61, CTGF …

The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling

B Perbal, C Martinerie, R Sainson… - Proceedings of the …, 1999 - National Acad Sciences
The NOVH protein belongs to the emerging CCN [Connective tissue growth factor (CTGF),
Cyr61/Cef10, nephroblastoma overexpressed gene] family of growth regulators sharing a …

Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells

S Gery, D Xie, D Yin, H Gabra, C Miller, H Wang… - Clinical cancer …, 2005 - AACR
Purpose: The connective tissue growth factor/cysteine-rich 61/nephroblastoma
overexpressed (CCN) family consists of six matricellular proteins that are involved in various …