Background Recently there has been an increase in Candida infections worldwide. A
handful of species in the genus Candida are opportunistic pathogens and have been known …

The epidemiology of Candida infections has changed in recent years. Although Candida
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …

Invasive fungal infections are an important infection concern for patients with underlying
immunosuppression. Antifungal therapy is a critical component of patient care, but …

OBJECTIVE: To summarize published data regarding mechanisms of reduced echinocandin
susceptibility in Candida spp., the impact of echinocandin resistance on the fitness and …

The incidence of serious fungal infections is increasing rapidly, and yet the rate of new drugs
becoming available to treat them is slow. The limited therapeutic armamentarium is a …

Echinocandins remain preferred agents against invasive Candida infections. Susceptibility
testing and FKS genotypic testing do not have roles in routine clinical practice, but may be …

Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …

In recent years, the relevance of diseases associated with fungal pathogens increased
worldwide. Members of the Candida genus are responsible for the greatest number of fungal …

This article addresses the emergence of echinocandin resistance among Candida species,
mechanisms of resistance, factors that promote resistance and confounding issues …

Background. Fluconazole (FLC) resistance is common in C. glabrata and echinocandins are
often used as first-line therapy. Resistance to echinocandin therapy has been associated …