Zwitterionic stealth peptide-protected gold nanoparticles enable long circulation without the accelerated blood clearance phenomenon

J Zhao, Z Qin, J Wu, L Li, Q Jin, J Ji - Biomaterials science, 2018 - pubs.rsc.org
Poly (ethylene glycol)(PEG), which is considered as a gold standard for surface modification
of nanoparticles in biomedical applications, has been reported to encounter the accelerated …

A higher dose of PEGylated gold nanoparticles reduces the accelerated blood clearance phenomenon effect and induces spleen B lymphocytes in albino mice

AM Abu-Dief, M Alsehli, A Awaad - Histochemistry and cell biology, 2022 - Springer
Polyethylene glycol (PEG) is a multifunctional polymer that has many uses in medical and
biological applications. Recently, PEG has been mainly used in developing nanomaterial …

Biologically inspired stealth peptide-capped gold nanoparticles

AK Nowinski, AD White, AJ Keefe, S Jiang - Langmuir, 2014 - ACS Publications
Introduction into the human body makes most nanoparticle systems susceptible to
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …

[HTML][HTML] Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

K Kalimuthu, BC Lubin, A Bazylevich… - Journal of …, 2018 - Springer
Abstract Background Peptide-drug-conjugates (PDCs) are being developed as an effective
strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges …

A lysine-rich cell penetrating peptide engineered multifunctional gold nanoparticle-based drug delivery system with enhanced cellular penetration and stability

N Devi, P Singh, R Sharma, M Kumar… - Journal of Materials …, 2022 - Springer
Engineered peptide-based drug delivery systems have gained substantial momentum in the
field of diagnostics and therapeutics owing to their superior biocompatibility, facilitation in …

Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment

A Kumar, H Ma, X Zhang, K Huang, S Jin, J Liu, T Wei… - Biomaterials, 2012 - Elsevier
Functionalization of nanostructures such as gold nanoparticles (AuNPs) with different
biological molecules has many applications in biomedical imaging, clinical diagnosis and …

One-pot synthesis of acid-induced in situ aggregating theranostic gold nanoparticles with enhanced retention in tumor cells

M Cheng, Y Zhang, X Zhang, W Wang, Z Yuan - Biomaterials science, 2019 - pubs.rsc.org
In this work, we took advantage of a one-pot reaction to prepare tumor-targeting
nanoparticles (Au@ T), which could respond to the intracellular acidic environment and form …

Cross-linked poly (ethylene glycol) shells for nanoparticles: enhanced stealth effect and colloidal stability

D Li, F Wang, H Di, X Liu, P Zhang, W Zhou, D Liu - Langmuir, 2019 - ACS Publications
Preventing protein corona formation and macrophage uptake is the key to improving the
delivery efficiency of nanocarriers. Herein, we present a kind of cross-linking poly (ethylene …

Enzyme-responsive multifunctional peptide coating of gold nanorods improves tumor targeting and photothermal therapy efficacy

L Wu, B Lin, H Yang, J Chen, Z Mao, W Wang, C Gao - Acta Biomaterialia, 2019 - Elsevier
It is well known that stealth coating effectively extends the circulation lifetime of
nanomaterials in blood, which favors systemic delivery but also limits their cellular …

Shuttling gold nanoparticles into tumoral cells with an amphipathic prolinerich peptide

S Pujals, NG Bastús, E Pereiro… - …, 2009 - Wiley Online Library
Golden bullets: The amphipathic prolinerich cellpenetrating peptide sweet arrow peptide
(SAP) is able to transport 12 nm gold nanoparticles efficiently into HeLa cells, as observed …