Zwitterionic stealth peptide-protected gold nanoparticles enable long circulation without the accelerated blood clearance phenomenon
J Zhao, Z Qin, J Wu, L Li, Q Jin, J Ji - Biomaterials science, 2018 - pubs.rsc.org
Poly (ethylene glycol)(PEG), which is considered as a gold standard for surface modification
of nanoparticles in biomedical applications, has been reported to encounter the accelerated …
of nanoparticles in biomedical applications, has been reported to encounter the accelerated …
A higher dose of PEGylated gold nanoparticles reduces the accelerated blood clearance phenomenon effect and induces spleen B lymphocytes in albino mice
Polyethylene glycol (PEG) is a multifunctional polymer that has many uses in medical and
biological applications. Recently, PEG has been mainly used in developing nanomaterial …
biological applications. Recently, PEG has been mainly used in developing nanomaterial …
Biologically inspired stealth peptide-capped gold nanoparticles
Introduction into the human body makes most nanoparticle systems susceptible to
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …
[HTML][HTML] Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells
Abstract Background Peptide-drug-conjugates (PDCs) are being developed as an effective
strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges …
strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges …
A lysine-rich cell penetrating peptide engineered multifunctional gold nanoparticle-based drug delivery system with enhanced cellular penetration and stability
Engineered peptide-based drug delivery systems have gained substantial momentum in the
field of diagnostics and therapeutics owing to their superior biocompatibility, facilitation in …
field of diagnostics and therapeutics owing to their superior biocompatibility, facilitation in …
Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment
Functionalization of nanostructures such as gold nanoparticles (AuNPs) with different
biological molecules has many applications in biomedical imaging, clinical diagnosis and …
biological molecules has many applications in biomedical imaging, clinical diagnosis and …
One-pot synthesis of acid-induced in situ aggregating theranostic gold nanoparticles with enhanced retention in tumor cells
M Cheng, Y Zhang, X Zhang, W Wang, Z Yuan - Biomaterials science, 2019 - pubs.rsc.org
In this work, we took advantage of a one-pot reaction to prepare tumor-targeting
nanoparticles (Au@ T), which could respond to the intracellular acidic environment and form …
nanoparticles (Au@ T), which could respond to the intracellular acidic environment and form …
Cross-linked poly (ethylene glycol) shells for nanoparticles: enhanced stealth effect and colloidal stability
D Li, F Wang, H Di, X Liu, P Zhang, W Zhou, D Liu - Langmuir, 2019 - ACS Publications
Preventing protein corona formation and macrophage uptake is the key to improving the
delivery efficiency of nanocarriers. Herein, we present a kind of cross-linking poly (ethylene …
delivery efficiency of nanocarriers. Herein, we present a kind of cross-linking poly (ethylene …
Enzyme-responsive multifunctional peptide coating of gold nanorods improves tumor targeting and photothermal therapy efficacy
L Wu, B Lin, H Yang, J Chen, Z Mao, W Wang, C Gao - Acta Biomaterialia, 2019 - Elsevier
It is well known that stealth coating effectively extends the circulation lifetime of
nanomaterials in blood, which favors systemic delivery but also limits their cellular …
nanomaterials in blood, which favors systemic delivery but also limits their cellular …
Shuttling gold nanoparticles into tumoral cells with an amphipathic prolinerich peptide
S Pujals, NG Bastús, E Pereiro… - …, 2009 - Wiley Online Library
Golden bullets: The amphipathic prolinerich cellpenetrating peptide sweet arrow peptide
(SAP) is able to transport 12 nm gold nanoparticles efficiently into HeLa cells, as observed …
(SAP) is able to transport 12 nm gold nanoparticles efficiently into HeLa cells, as observed …