Effect of the Nicotinic α4β2-receptor Partial Agonist Varenicline on Non-invasive Brain Stimulation-Induced Neuroplasticity in the Human Motor Cortex

G Batsikadze, W Paulus, J Grundey, MF Kuo… - Cerebral …, 2015 - academic.oup.com
Nicotine alters cognitive functions in animals and humans most likely by modification of
brain plasticity. In the human brain, it alters plasticity induced by transcranial direct current …

Compromised neuroplasticity in cigarette smokers under nicotine withdrawal is restituted by the nicotinic α4β2-receptor partial agonist varenicline

G Batsikadze, W Paulus, A Hasan, J Grundey… - Scientific reports, 2017 - nature.com
Nicotine modulates neuroplasticity and improves cognitive functions in animals and
humans. In the brain of smoking individuals, calcium-dependent plasticity induced by non …

Nicotinergic impact on focal and non-focal neuroplasticity induced by non-invasive brain stimulation in non-smoking humans

N Thirugnanasambandam, J Grundey… - …, 2011 - nature.com
Nicotine improves cognitive performance and modulates neuroplasticity in brain networks.
The neurophysiological mechanisms underlying nicotine-induced behavioral changes have …

Mechanisms of nicotinic modulation of glutamatergic neuroplasticity in humans

MDMV Lugon, G Batsikadze, S Fresnoza… - Cerebral …, 2017 - academic.oup.com
The impact of nicotine (NIC) on plasticity is thought to be primarily determined via calcium
channel properties of nicotinic receptor subtypes, and glutamatergic plasticity is likewise …

Nicotine modulates human brain plasticity via calciumdependent mechanisms

J Grundey, J Barlay, G Batsikadze… - The Journal of …, 2018 - Wiley Online Library
Key points Nicotine (NIC) modulates cognition and memory function by targeting the
nicotinic ACh receptor and releasing different transmitter systems postsynaptically. With both …

Rapid effect of nicotine intake on neuroplasticity in non-smoking humans

J Grundey, N Thirugnanasambandam… - Frontiers in …, 2012 - frontiersin.org
In various studies nicotine has shown to alter cognitive functions in non-smoking subjects.
The physiological basis for these effects might be nicotine-generated modulation of cortical …

Neuroplasticity in cigarette smokers is altered under withdrawal and partially restituted by nicotine exposition

J Grundey, N Thirugnanasambandam… - Journal of …, 2012 - Soc Neuroscience
Nicotine improves cognitive functions by modulating neuroplasticity and cortical excitability
in nonsmoking subjects. As shown recently, the positive effect of nicotine on cognition might …

Nicotinic restoration of excitatory neuroplasticity is linked to improved implicit motor learning skills in deprived smokers

J Grundey, N Thirugnasambandam, R Amu… - Frontiers in …, 2018 - frontiersin.org
Nicotine has been shown to modulate neuroplasticity, cognition, and learning processes in
smokers and non-smokers. A possible mechanism for its effect on learning and memory …

Catecholaminergic consolidation of motor cortical neuroplasticity in humans

MA Nitsche, J Grundey, D Liebetanz, N Lang… - Cerebral …, 2004 - academic.oup.com
Amphetamine, a catecholaminergic re-uptake-blocker, is able to improve neuroplastic
mechanisms in humans. However, so far not much is known about the underlying …

Focusing effect of acetylcholine on neuroplasticity in the human motor cortex

MF Kuo, J Grosch, F Fregni, W Paulus… - Journal of …, 2007 - Soc Neuroscience
Cholinergic neuromodulation is pivotal for arousal, attention, and cognitive processes. Loss
or dysregulation of cholinergic inputs leads to cognitive impairments like those manifested in …